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109333 Pkn2

109333

Pkn2

protein kinase N2

protein-coding

Mus musculus

基因描述

Type Description
Definition protein kinase N2

研究结论

Date Results Publications
2020-11-28 13:11:00 Novel roles of PRK1 and PRK2 in cilia and cancer biology. 32127582
2020-07-04 12:33:00 PKN1 and PKN2 activation causes cardiac dysfunction and is involved in the transition to heart failure by phosphorylating MRTFA and disrupting its interaction with actin. 31564129
2017-10-14 12:53:00 In mature skeletal muscle, in vivo PKN2 knockdown decreased glucose uptake and increased AMPK phosphorylation. Thus, PKN2 alters key signaling pathways and transcriptional networks to regulate glucose and lipid metabolism. 28720584
2017-08-26 11:36:00 Mechanistically, Yersinia pseudotuberculosis YopM recruits and activates the mouse host kinases PRK1 and PRK2 to negatively regulate pyrin by phosphorylation. 27569559
2017-08-05 10:55:00 PKN2 formed complexes with Cdo, APPL1 and AKT via its C-terminal region and this interaction appeared to be important for induction of AKT activity as well as myoblast differentiation. 27763641

名称对应

Type IDs
Synonymous 6030436C20Rik, AI507382, PRK2, Prkcl2, Stk7
Gene
UniProtKB-ID: PKN2_MOUSE
UniprotKB: Q8BWW9
UniParc: UPI000019269C, UPI0001F78E4F, UPI00005AB971
EMBL: AK049713, BC052073, AK171092, AK083425, AK046248, AK133298
Ensembl: ENSMUSG00000004591
KO: mmu:109333
Nucleutide sequences
EMBL-CDS: BAC32655.1, AAH52073.1, BAE21599.1, BAE42244.1, BAC38910.1, BAC33888.1
Ensembl_TRS: ENSMUST00000043812
Protein sequencees
Ensembl_PRO: ENSMUSP00000039566
RefSeq: NP_848769.2
Others
UniRef100: UniRef100_Q8BWW9
UniRef90: UniRef90_Q16513
UniRef50: UniRef50_Q16513
UniGene: Mm.244236
CCDS: CCDS51084.1

全选

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研究热度

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