| Type | Description |
|---|---|
| Definition | ring finger protein 20 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 11:44:00 | RNF20 promoted proteasomal degradation of nuclear corepressor 1 (NCoR1), which led to stimulation of the transcriptional activity of PPARgamma. Collectively, these data suggest that RNF20-NCoR1 is a novel axis in adipocyte biology through fine-tuning the transcriptional activity of PPARgamma. | 31604693 |
| 2020-04-04 11:56:00 | These data suggest that Rnf20 functions at the Rfx3 locus regulating cilia motility and cardiac situs and identify H2Bub1 as an upstream transcriptional regulator controlling tissue-specific expression of cilia genes. Our findings mechanistically link the two functional gene ontologies that have been implicated in human CHD: chromatin remodeling and cilia function. | 31235600 |
| 2020-03-21 12:29:00 | The E3 ubiquitin ligases ring finger protein 20 (RNF20) regulates transcription through imparting monoubiquitin marks on histone H2B (H2Bub1), a precursor to histone H3 lysine 4 trimethylation (H3K4me3). Rnf20 depletion reduces beta-cell H2Bub1 marks and uncovered several target genes, including glucose transporter 2 (Glut2), MAF BZIP transcription factor A (MafA), and uncoupling protein 2 (Ucp2). | 31186351 |
| 2019-11-09 11:25:00 | Results suggest that RNF20, RNF40, and H2Bub may represent a novel pathway for DSB sensing and repair. | 30692271 |
| 2017-10-21 10:24:00 | The results demonstrate that Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B monoubiquitination. | 28453857 |
| Type | IDs |
|---|---|
| Synonymous | 4833430L21Rik, AW540162, C79397, mKIAA4116 |
| Gene |
UniProtKB-ID:
BRE1A_MOUSE
UniprotKB:
Q5DTM8
UniParc:
UPI000019B06A,
UPI00006275C8
EMBL:
AK051278,
AK085436,
AK139883,
AK048862,
AK076501,
BC052482,
AL732521,
AK053783,
AK220492
Ensembl:
ENSMUSG00000028309
KO:
mmu:109331
|
| Nucleutide sequences |
EMBL-CDS:
BAC35521.1,
AAH52482.1,
BAC39446.1,
BAE24170.1,
BAC34590.2,
BAC36367.1,
BAD90290.1,
BAE43337.1
Ensembl_TRS:
ENSMUST00000029989,
ENSMUST00000167496
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029989,
ENSMUSP00000128546
RefSeq:
NP_001343330.1,
NP_892044.1,
XP_011248208.1,
NP_001156735.1,
XP_036019474.1,
XP_006537616.1,
XP_030108941.1,
XP_036019473.1
|
| Others |
UniRef100:
UniRef100_Q5DTM8
UniRef90:
UniRef90_Q5DTM8
UniRef50:
UniRef50_Q5VTR2
UniGene:
Mm.24765
CCDS:
CCDS18178.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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