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10933 MORF4L1

10933

MORF4L1

mortality factor 4 like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition mortality factor 4 like 1

研究结论

Date Results Publications
2020-06-13 12:58:00 ASH1L activation by MRG15 represents a delicate regulatory mechanism for how a cofactor activates an SET domain HMTase by releasing autoinhibition 30827841
2020-06-13 12:58:00 Ash1L stimulates H3K36 methyltransferase activity through Mrg15 binding 30827843
2018-06-09 10:04:00 PALB2 associates with active genes through its major binding partner, MRG15, which recognizes histone H3 trimethylated at lysine 36 (H3K36me3) by the SETD2 methyltransferase 28673974
2013-01-26 10:48:00 Both MRG15 CD and Pf1 PHD1 bind to their targets with >100 muM affinity. 22728643
2012-05-26 10:46:00 While the present study expands on the role of MRG15 in the control of genomic stability, weak associations can not be ruled out for potential low-penetrance variants at MORF4L1 and breast cancer risk among BRCA2 mutation carriers 21466675

名称对应

Type IDs
Synonymous Eaf3, FWP006, HsT17725, MEAF3, MORFRG15, MRG15, S863-6
Gene
UniProtKB-ID: MO4L1_HUMAN
UniprotKB: Q9UBU8
UniParc: UPI0000000A79, UPI000000D82F, UPI000060771A
EMBL: AF161546, BC002936, BC067826, AK296650, CH471136, AF218011, AL137697, AC011944, AF109188, AC103975, BC022845, AF167173, AC022748, CX165647, AY148481, AK300789, AF100615, AF070664, AF131847
Ensembl: ENSG00000185787
KO: hsa:10933
Nucleutide sequences
EMBL-CDS: EAW99144.1, AAD20970.1, AAD20058.1, AAN65338.1, AAD29872.1, EAW99146.1, BAG59248.1, AAH67826.1, BAH13347.1, AAF80854.1, CAB70879.2, AAQ13497.1, EAW99147.1, EAW99145.1, AAH22845.1, AAF29033.1, AAH02936.1, AAG17253.1
Gene_ORFName: PP368, HSPC061, FWP006, HSPC008
Ensembl_TRS: ENST00000426013, ENST00000559345, ENST00000558502, ENST00000331268
Protein sequencees
Ensembl_PRO: ENSP00000408880, ENSP00000452717, ENSP00000331310, ENSP00000452808
RefSeq: NP_001252534.1, NP_996670.1, NP_001252532.1, NP_001252533.1, NP_006782.1
Others
UniRef100: UniRef100_Q9UBU8
UniRef90: UniRef90_Q9UBU8
UniRef50: UniRef50_Q9UBU8
UniGene: Hs.374503
CCDS: CCDS58393.1, CCDS32304.1, CCDS10307.1

全选

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研究热度

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