| Type | Description |
|---|---|
| Definition | ORAI calcium release-activated calcium modulator 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:32:00 | Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling. | 32354146 |
| 2020-12-19 13:43:00 | ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense. | 32929002 |
| 2020-11-21 13:16:00 | GPR40 activation initiates store-operated Ca(2+) entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic beta-cells. | 31664108 |
| 2020-09-26 13:08:00 | Loss of Ca(2+) entry via Orai-TRPC1 induces ER stress, initiating immune activation in macrophages. | 31722977 |
| 2020-07-04 11:45:00 | findings suggest a key role of cardiac Orai1 channels and the potential for Orai1 channel inhibitors as inotropic therapies for maintaining contractility reserve after hypertrophic stress. | 31906693 |
| Type | IDs |
|---|---|
| Synonymous | D730049H07Rik, Tmem142a, orai-1 |
| Gene |
UniProtKB-ID:
CRCM1_MOUSE,
A3KCG1_MOUSE
UniprotKB:
Q8BWG9,
A3KCG1
UniParc:
UPI00000EA7C6
EMBL:
AM712355,
AK052573,
BC023149,
AK085755,
AB271214
Ensembl:
ENSMUSG00000049686
KO:
mmu:109305
|
| Nucleutide sequences |
EMBL-CDS:
BAC35045.1,
BAC39533.1,
AAH23149.1,
CAN36426.1,
BAF47905.1
Ensembl_TRS:
ENSMUST00000051016,
ENSMUST00000121652
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113097,
ENSMUSP00000058169
RefSeq:
XP_006530180.1,
NP_780632.1,
XP_006530179.1
|
| Others |
UniRef100:
UniRef100_Q8BWG9
UniRef90:
UniRef90_Q8BWG9
UniRef50:
UniRef50_Q8BWG9
UniGene:
Mm.218582
CCDS:
CCDS39261.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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