| Type | Description |
|---|---|
| Definition | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 10:57:00 | complex signaling mechanisms that involve PREX2, PI3K/AKT/PTEN and downstream epigenetic machinery to deregulate expression of key cell cycle regulators | 27111337 |
| 2014-03-15 10:07:00 | P-REX2 PH-domain-mediated inhibition of PTEN has a role in regulating insulin sensitivity and glucose homeostasis | 24367090 |
| 2013-11-02 11:43:00 | This study demonistrated that the P-Rex2, a GEF that specifically activates Rac small GTPases, is expressed in a cell- and synapse-specific manner in the retina. | 23844743 |
| 2010-11-06 10:16:00 | PI3K/P-Rex/Rac pathway is required for late phase long-term potentiation in the mouse cerebellum | 20694145 |
| 2010-01-21 00:00:00 | P-Rex1 and P-Rex2 are important regulators of Purkinje cell morphology and cerebellar function | 18334636 |
| Type | IDs |
|---|---|
| Synonymous | 6230420N16Rik, AI316880, AI553603, C030045D06Rik, D430013K02, Depdc2, P-Rex2 |
| Gene |
UniProtKB-ID:
PREX2_MOUSE,
Q3UWW3_MOUSE
UniprotKB:
Q3LAC4,
Q3UWW3
UniParc:
UPI0000D8ABA7,
UPI00001E2D9C,
UPI00001C20CA
EMBL:
AM109952,
AK018093,
AK138884,
AK136059,
AC102481,
BC139253,
BC139255,
AC102631,
AC102529,
AK142414,
AC164600
Ensembl:
ENSMUSG00000048960
KO:
mmu:109294
|
| Nucleutide sequences |
EMBL-CDS:
BAE23811.1,
CAJ33348.1,
BAB31066.1,
BAE25059.1,
AAI39256.1,
BAE22801.1,
AAI39254.1
Ensembl_TRS:
ENSMUST00000027056
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027056
RefSeq:
XP_036008977.1,
XP_006495504.1,
NP_083801.1,
XP_036008968.1,
NP_001028808.1
|
| Others |
UniRef100:
UniRef100_Q3UWW3,
UniRef100_Q3LAC4
UniRef90:
UniRef90_Q3LAC4,
UniRef90_A0A091CRB3
UniRef50:
UniRef50_K7GGJ1,
UniRef50_Q70Z35
UniGene:
Mm.123247
CCDS:
CCDS48217.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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