| Type | Description |
|---|---|
| Definition | DBF4 zinc finger |
| Date | Results | Publications |
|---|---|---|
| 2019-08-10 12:15:00 | High DBF4 expression is associated with oral cancer. | 29209046 |
| 2019-02-02 10:14:00 | CDC7-DBF4 kinase (DDK) has a primary role in the replication checkpoint to promote single-stranded DNA accumulation at stalled forks, which is required to initiate a robust checkpoint response and cell cycle arrest to maintain genome integrity. | 30157471 |
| 2018-02-24 11:45:00 | Both CDC7 and DBF4 promoters bind E2F, suggesting that increased E2F activity in RB1 mutant cancers promotes increased DDK expression. Surprisingly, increased DDK expression levels are also correlated with both increased chemoresistance and genome-wide mutation frequencies. | 28448802 |
| 2017-06-24 11:43:00 | Histone H3 lysine 9 (H3K9) acetylation was most prevalent when the Dbf4 transcription level was highest whereas the H3K9me3 level was greatest during and just after replication. | 27341472 |
| 2017-06-10 12:13:00 | we propose that phosphorylation of TOP2A by CDC7/DBF4 in early S-phase prevents its localization and/or activity at centromeres, and inhibition of TOP2A function could be relevant to prevent premature separation of centromeric DNA. | 27407105 |
| Type | IDs |
|---|---|
| Synonymous | ASK, CHIF, DBF4A, ZDBF1 |
| Gene |
UniProtKB-ID:
DBF4A_HUMAN,
B4DXK0_HUMAN,
B7Z8C6_HUMAN
UniprotKB:
Q9UBU7,
B4DXK0,
B7Z8C6
UniParc:
UPI0000EE57C1,
UPI0000070234,
UPI00017A8190,
UPI000000DC33
EMBL:
AK292569,
BC036045,
AB028069,
AC003083,
AK302010,
AB028070,
AK303175,
BC047693,
AF160876,
AF160249,
CH236949,
AC005164,
CH471091
Ensembl:
ENSG00000006634
KO:
hsa:10926
|
| Nucleutide sequences |
EMBL-CDS:
AAS07418.1,
BAA78327.1,
BAF85258.1,
AAS07442.1,
EAL24170.1,
BAA78326.1,
EAW76930.1,
AAH47693.1,
AAD45357.1,
AAH36045.1,
AAD41911.1,
BAG63412.1,
EAW76931.1,
BAH13912.1
Gene_ORFName:
hCG_2023664
Ensembl_TRS:
ENST00000413643,
ENST00000265728,
ENST00000430279
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265728,
ENSP00000414083,
ENSP00000389397
RefSeq:
NP_001304989.1,
NP_001304991.1,
NP_001304990.1,
NP_006707.1
|
| Others |
UniRef100:
UniRef100_B4DXK0,
UniRef100_Q9UBU7
UniRef90:
UniRef90_B4DXK0,
UniRef90_Q9UBU7
UniRef50:
UniRef50_A0A5N3XPT9,
UniRef50_Q9UBU7
UniGene:
Hs.485380
CCDS:
CCDS5611.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员