| Type | Description |
|---|---|
| Definition | poly(A) polymerase alpha |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 13:29:00 | Whereas PABPN1 strongly increases the activity of its cognate poly(A) polymerase in vitro, Pab2 was unable to stimulate Pla1 to any significant extent. | 28096519 |
| 2016-06-28 10:41:00 | Lack of CstF-64 binding excludes PAPalpha from Star-PAP target pre-mRNA UTRs.CstF-64 and 3'-UTR cis-element determine Star-PAP specificity for target mRNA selection by excluding poly A polymerase. | 26496945 |
| 2015-08-22 10:30:00 | The ability of PABPN1 to promote splicing requires its RNA binding and, to a lesser extent, poly(A)polymerase (PAP) - stimulatory functions. | 25896913 |
| 2010-09-27 11:51:00 | Observations imply that translational regulation is among the conserved mechanisms regulating PAPOLA expression. | 20174964 |
| Type | IDs |
|---|---|
| Synonymous | PAP, PAP-alpha |
| Gene |
UniProtKB-ID:
PAPOA_HUMAN,
A0A024R6M3_HUMAN,
A0A024R6J7_HUMAN,
A0A0C4DGK1_HUMAN
UniprotKB:
P51003,
A0A024R6M3,
A0A024R6J7,
A0A0C4DGK1
UniParc:
UPI0000074269,
UPI000000CC90,
UPI0000EE33E8,
UPI000000CC6A
EMBL:
X76770,
BC000927,
AL163051,
CH471061,
BC036014,
BX248753,
BX161482,
BX248301
Ensembl:
ENSG00000090060
KO:
hsa:10914
|
| Nucleutide sequences |
EMBL-CDS:
CAD66560.1,
CAD62628.1,
AAH36014.1,
CAD61935.1,
AAH00927.1,
EAW81642.1,
EAW81644.1,
EAW81647.1,
EAW81643.1,
EAW81648.1
Gene_ORFName:
hCG_24516,
hCG_24516,
hCG_24516
Ensembl_TRS:
ENST00000557320,
ENST00000216277,
ENST00000557471
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000450437,
ENSP00000216277,
ENSP00000450812
RefSeq:
NP_001350594.1,
NP_001280556.1,
NP_001350593.1,
NP_001350591.1,
NP_001280557.1,
NP_001238936.1,
NP_001280561.1,
NP_001350595.1,
NP_116021.2,
NP_001238935.1
|
| Others |
UniRef100:
UniRef100_A0A0C4DGK1,
UniRef100_P51003,
UniRef100_A0A024R6J7
UniRef90:
UniRef90_P25500,
UniRef90_A0A2K6M0D0,
UniRef90_P51003
UniRef50:
UniRef50_P25500,
UniRef50_A0A2K6M0D0,
UniRef50_P51003
UniGene:
Hs.253726
CCDS:
CCDS58334.1,
CCDS9946.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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