| Type | Description |
|---|---|
| Definition | ubiquitin-like, containing PHD and RING finger domains 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-06 09:57:00 | During limb development in mouse embryos, Uhrf2 is expressed in the undifferentiated autopodial mesoderm and in subsequent stages, expression becomes restricted to the interdigital mesoderm. By day 14 post coitum, interdigit regression is almost accomplished and Uhrf gene expression become restricted to zones of the joint formation. | 31024001 |
| 2019-03-02 12:12:00 | These results suggested that Uhrf2 deletion selectively blocked the development of the DG crest and impaired hippocampus-dependent learning and memory. Our study will facilitate a better understanding of the role of Uhrf2 protein in the central nervous system. | 28900727 |
| 2017-12-09 11:42:00 | 5mC levels are decreased at certain genomic loci in the brains of Uhrf2 knockout mice. UHRF KO mice develop frequent spontaneous seizures. | 28402695 |
| 2017-06-10 12:01:00 | Uhrf2 null mice exhibit a reduction of 5-Hydroxymethylcytosine in the brain, including the cortex and hippocampus. Furthermore, the Uhrf2 null mice exhibit a partial impairment in spatial memory acquisition and retention. | 28115522 |
| 2014-01-18 10:37:00 | Uhrf2 is highly expressed in aorta and aortic vascular smooth muscle cells. | 24134842 |
| Type | IDs |
|---|---|
| Synonymous | 2310065A22Rik, AI426270, AW214556, D130071B19Rik, Nirf |
| Gene |
UniProtKB-ID:
UHRF2_MOUSE
UniprotKB:
Q7TMI3
UniParc:
UPI0000022454,
UPI00000EBA58,
UPI00000EB691
EMBL:
AK051743,
AB116653,
BC060241,
AK031036,
AK042321,
AK080925,
AF274047,
AK041564
Ensembl:
ENSMUSG00000024817
KO:
mmu:109113
|
| Nucleutide sequences |
EMBL-CDS:
BAC81739.1,
BAC34750.1,
BAC38081.1,
AAM33798.1,
BAC31223.1,
BAC27224.1,
AAH60241.1,
BAC30987.1
Ensembl_TRS:
ENSMUST00000025739
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025739
RefSeq:
NP_659122.2,
XP_036017292.1,
XP_006526666.1,
XP_036017291.1
|
| Others |
UniRef100:
UniRef100_Q7TMI3
UniRef90:
UniRef90_Q7TMI3
UniRef50:
UniRef50_Q7TMI3
UniGene:
Mm.313364
CCDS:
CCDS37955.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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