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10901 DHRS4

10901

DHRS4

dehydrogenase/reductase 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition dehydrogenase/reductase 4

研究结论

Date Results Publications
2017-02-18 11:37:00 An analysis of the relationship between the promoter characteristics and RNA expression of the DHRS4 gene cluster indicated that the development of CpG islands, in addition to the promoter sequence, during mammalian evolution could modulate the dose compensatory regulation of the copy number-varied DHRS4 gene cluster 27323117
2016-12-17 11:48:00 AS1eRNA-driven DNA looping and activating histone modifications promote the expression of DHRS4-AS1 to economically control the DHRS4 gene cluster. 26864944
2013-06-01 12:00:00 NRDRB1, an alternatively spliced isoform of NRDR in vivo functions better than NRDR as a dicarbonyl reductase for xenobiotics containing reactive carbonyls. 23128527
2013-04-11 13:39:00 Results suggest a novel mechanism of cold inactivation and role of the inducible human DHRS4 in 3beta-hydroxysteroid synthesis and xenobiotic carbonyl metabolism 18571493
2013-04-11 13:37:00 DHRS2 and DHRS4 genes are syntenic outparalogues originating from a duplication of the DHRS4 gene that took place before the formation of the mammalian clade 23036705

名称对应

Type IDs
Synonymous CR, NRDR, PHCR, PSCD, SCAD-SRL, SDR-SRL, SDR25C1, SDR25C2
Gene
UniProtKB-ID: DHRS4_HUMAN
UniprotKB: Q9BTZ2
UniParc: UPI000068309A, UPI0000D6A63C, UPI000003F541, UPI0001E24F25, UPI000013F4B8, UPI0001642860, UPI0001E24F24, UPI000013F4B3
EMBL: AK001870, DQ325464, BC003019, AY071856, AL136419, AY358638, AF044127, AY616182, AB045131, AF064256, AK314448, DQ338571, DQ344810, AY943857
Ensembl: ENSG00000157326, ENSG00000284807
KO: hsa:10901
Nucleutide sequences
EMBL-CDS: AAQ13444.1, AAD02292.1, ABC61321.1, AAQ89001.1, BAG37057.1, ABD75823.1, AAX49568.1, AAH03019.1, ABC61320.1, BAB18775.1, AAL61824.2, BAA91953.1, AAT70757.1
Gene_ORFName: UNQ851/PRO1800
Ensembl_TRS: ENST00000647030, ENST00000645612, ENST00000558263, ENST00000647154, ENST00000645602, ENST00000559632, ENST00000646997, ENST00000643978, ENST00000558581, ENST00000397074, ENST00000397075, ENST00000313250
Protein sequencees
Ensembl_PRO: ENSP00000380264, ENSP00000495868, ENSP00000494364, ENSP00000453983, ENSP00000380265, ENSP00000452645, ENSP00000493736, ENSP00000496349, ENSP00000453367, ENSP00000326219, ENSP00000495877, ENSP00000496426
RefSeq: NP_066284.2, NP_001269917.1, XP_011534668.1, NP_001269918.1, XP_006720068.1, NP_001269919.1, NP_001269916.1, NP_001269920.1
Others
UniRef100: UniRef100_Q9BTZ2
UniRef90: UniRef90_Q9BTZ2
UniRef50: UniRef50_Q9BTZ2
UniGene: Hs.528385
CCDS: CCDS9605.1, CCDS61411.1, CCDS61409.1, CCDS61412.1, CCDS61410.1, CCDS61408.1

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