Type | Description |
---|---|
Definition | jumping translocation breakpoint |
Date | Results | Publications |
---|---|---|
2013-06-29 12:46:00 | Downregulation of the PAR expression increases the Bax/Bcl-2 ratio and Bax expression, and thus induces the G2-M phase arrest and apoptosis of PC3 cells. | 23297497 |
2013-01-12 10:02:00 | Silencing of the JTB resulted in an increase in the phosphorylation of p65 in HepG2 cells. | 22615844 |
2012-05-12 10:05:00 | The JTB structure has a distant relationship to the midkine/pleiotrophin fold, particularly in the conservation of distinctive disulfide bridge patterns. | 22079049 |
2011-06-18 10:10:00 | Due to its involvement in cell cycle and its overexpression in several human cancers PAR could represent an attractive target for therapeutic intervention. | 21225229 |
2010-01-21 00:00:00 | Overexpression of JTB conferred resistance to apoptosis induced by ultraviolet radiation | 19487072 |
Type | IDs |
---|---|
Synonymous | HJTB, HSPC222, PAR, hJT |
Gene |
UniProtKB-ID:
JTB_HUMAN
UniprotKB:
O76095
UniParc:
UPI000012DACC,
UPI0000073D1F
EMBL:
BC001667,
CR456985,
BT007285,
BC000499,
AB016492,
BC000996,
AF151056,
CH471121,
AB016488,
BC019277,
BC001363,
AL358472,
BC004239,
AB016493,
AF115850,
AK312106,
AF131797
Ensembl:
ENSG00000143543
KO:
hsa:10899
|
Nucleutide sequences |
EMBL-CDS:
EAW53241.1,
BAA33731.1,
AAH19277.1,
AAF36142.1,
BAA33736.1,
AAH01363.1,
EAW53242.1,
CAG33266.1,
BAG35042.1,
EAW53244.1,
AAH04239.1,
AAD09822.2,
AAD20045.1,
BAA33735.1,
AAH00996.1,
AAP35949.1,
AAH00499.1,
AAH01667.1
Gene_ORFName:
HSPC222
Ensembl_TRS:
ENST00000368589,
ENST00000428469,
ENST00000356648,
ENST00000271843
|
Protein sequencees |
Ensembl_PRO:
ENSP00000357578,
ENSP00000395250,
ENSP00000271843,
ENSP00000349069
RefSeq:
NP_006685.1
|
Others |
UniRef100:
UniRef100_O76095
UniRef90:
UniRef90_O76095
UniRef50:
UniRef50_O76095
UniGene:
Hs.6396
CCDS:
CCDS1057.1
|
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---|---|---|---|---|---|---|---|---|
Refseq |
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