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10899 JTB

10899

JTB

jumping translocation breakpoint

protein-coding

Homo sapiens

基因描述

Type Description
Definition jumping translocation breakpoint

研究结论

Date Results Publications
2013-06-29 12:46:00 Downregulation of the PAR expression increases the Bax/Bcl-2 ratio and Bax expression, and thus induces the G2-M phase arrest and apoptosis of PC3 cells. 23297497
2013-01-12 10:02:00 Silencing of the JTB resulted in an increase in the phosphorylation of p65 in HepG2 cells. 22615844
2012-05-12 10:05:00 The JTB structure has a distant relationship to the midkine/pleiotrophin fold, particularly in the conservation of distinctive disulfide bridge patterns. 22079049
2011-06-18 10:10:00 Due to its involvement in cell cycle and its overexpression in several human cancers PAR could represent an attractive target for therapeutic intervention. 21225229
2010-01-21 00:00:00 Overexpression of JTB conferred resistance to apoptosis induced by ultraviolet radiation 19487072

名称对应

Type IDs
Synonymous HJTB, HSPC222, PAR, hJT
Gene
UniProtKB-ID: JTB_HUMAN
UniprotKB: O76095
UniParc: UPI000012DACC, UPI0000073D1F
EMBL: BC001667, CR456985, BT007285, BC000499, AB016492, BC000996, AF151056, CH471121, AB016488, BC019277, BC001363, AL358472, BC004239, AB016493, AF115850, AK312106, AF131797
Ensembl: ENSG00000143543
KO: hsa:10899
Nucleutide sequences
EMBL-CDS: EAW53241.1, BAA33731.1, AAH19277.1, AAF36142.1, BAA33736.1, AAH01363.1, EAW53242.1, CAG33266.1, BAG35042.1, EAW53244.1, AAH04239.1, AAD09822.2, AAD20045.1, BAA33735.1, AAH00996.1, AAP35949.1, AAH00499.1, AAH01667.1
Gene_ORFName: HSPC222
Ensembl_TRS: ENST00000368589, ENST00000428469, ENST00000356648, ENST00000271843
Protein sequencees
Ensembl_PRO: ENSP00000357578, ENSP00000395250, ENSP00000271843, ENSP00000349069
RefSeq: NP_006685.1
Others
UniRef100: UniRef100_O76095
UniRef90: UniRef90_O76095
UniRef50: UniRef50_O76095
UniGene: Hs.6396
CCDS: CCDS1057.1

全选

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