| Type | Description |
|---|---|
| Definition | interleukin-1 receptor-associated kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:32:00 | IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes. | 32778760 |
| 2020-06-13 12:39:00 | miR-497 can partially negatively regulate the activation of IRAK2-NF-kappaB pathway in LPS-induced inflammatory responses | 31148190 |
| 2018-06-23 10:08:00 | In summary, lipopolysaccharide activates a nuclear function of IRAK2 that facilitates the assembly of nuclear export machinery to export selected inflammatory mRNAs to the cytoplasm for translation. | 28990926 |
| 2014-01-11 11:08:00 | These findings demonstrate an unexpected linkage of the innate immunity machinery to unfolded protein response signaling, revealing IRAK2 as a novel amplifier of the IRE1 pathway. | 23724040 |
| 2013-11-16 12:27:00 | Our results establish that the IRAK2-TRAF6 interaction is rate limiting for the late, but not the early phase of cytokine production in bone marrow-derived macrophages and plasmacytoid dendritic cells | 23918981 |
| Type | IDs |
|---|---|
| Synonymous | 6330415L08Rik, AI649099, IRAK-2 |
| Gene |
UniProtKB-ID:
IRAK2_MOUSE
UniprotKB:
Q8CFA1
UniParc:
UPI000000D088,
UPI0000EF888F,
UPI0000D6280B,
UPI0000195AE1
EMBL:
AY162379,
AK150056,
AJ440756,
AY162380,
AK152682,
AK154715,
AY162381,
AK033707,
BC085324,
AK148248,
AY162378,
AK028733,
AK078062,
AK151428
Ensembl:
ENSMUSG00000060477
KO:
mmu:108960
|
| Nucleutide sequences |
EMBL-CDS:
BAC37114.1,
BAE31414.1,
CAD29447.2,
BAE30392.1,
AAO24763.1,
AAH85324.1,
BAC26088.1,
AAO24762.1,
AAO24764.1,
BAC28438.1,
BAE32783.1,
BAE29271.1,
BAE28437.1,
AAO24761.1
Ensembl_TRS:
ENSMUST00000059286,
ENSMUST00000089022,
ENSMUST00000089023
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000086417,
ENSMUSP00000055073,
ENSMUSP00000086416
RefSeq:
XP_006505388.1,
NP_001107025.1,
NP_751893.3
|
| Others |
UniRef100:
UniRef100_Q8CFA1
UniRef90:
UniRef90_Q8CFA1
UniRef50:
UniRef50_Q8CFA1
UniGene:
Mm.152142
CCDS:
CCDS51873.1,
CCDS20430.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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