| Type | Description |
|---|---|
| Definition | mitoguardin 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-16 10:19:00 | The ovarian phenotypes of these mice suggested that the MIGA1/2 proteins play an important role in ovulation and ovarian steroidogenesis. In vivo and in vitro analyses of Miga1/2-knockout granulosa cells showed severe defects in luteinization and steroidogenesis and disordered mitochondrial morphology and function in response to gonadotropins. | 28938432 |
| 2016-12-17 11:28:00 | Data indicate that mitoguardin (Miga) knoskout Miga1/2-/- females show greatly reduced quality of oocytes and early embryos and are subfertile. | 26716412 |
| 2016-08-11 09:22:00 | Propose that MIGA1/2 proteins promote mitochondrial fusion by regulating mitochondrial phospholipid metabolism via MitoPLD. | 26711011 |
| Type | IDs |
|---|---|
| Synonymous | 5730472N09Rik, AA408683, AI790341, C9orf54, Fam73b, R74766 |
| Gene |
UniProtKB-ID:
MIGA2_MOUSE
UniprotKB:
Q8BK03
UniParc:
UPI00000EB630,
UPI00005ABF75
EMBL:
AL954388,
AK077618,
BC051404,
AK154200,
AK140122
Ensembl:
ENSMUSG00000026858
KO:
mmu:108958
|
| Nucleutide sequences |
EMBL-CDS:
BAC36904.1,
BAE24244.1,
AAH51404.1,
BAE32434.1
Ensembl_TRS:
ENSMUST00000100214,
ENSMUST00000077977,
ENSMUST00000140075
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000135519,
ENSMUSP00000097787,
ENSMUSP00000077127
RefSeq:
NP_001365835.1,
NP_001365838.1,
NP_001229336.1,
XP_030102435.1,
NP_001365836.1,
XP_006497656.1,
XP_006497657.1,
NP_780601.1,
NP_001365840.1
|
| Others |
UniRef100:
UniRef100_Q8BK03
UniRef90:
UniRef90_Q8BK03
UniRef50:
UniRef50_Q7L4E1
UniGene:
Mm.254974
CCDS:
CCDS15880.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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