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10878 CFHR3

10878

CFHR3

complement factor H related 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition complement factor H related 3

研究结论

Date Results Publications
2020-09-26 13:02:00 Deletions in Genes Participating in Innate Immune Response Modify the Clinical Course of Andes Orthohantavirus Infection. 31349540
2020-08-01 10:17:00 These findings provide a mechanistic explanation as to why the deletion of CFHR3 and CFHR1 is protective in AMD and highlight the importance of genetic variants within the CFH/CFHR3/CFHR1 locus in the recognition of altered-self in tissue homeostasis. 32321835
2020-02-08 10:45:00 Overexpression of CFHR3 suppressed proliferation and promoted apoptosis of HCC cells by inhibiting the PI3K/Akt/mTOR signaling pathway. 31524260
2019-07-13 12:28:00 In conclusion, the CFHR3,1D genotype did not associate with progression toward CKD stages 3 and 5 in our white population of patients with IgAN, although it did associate with a reduced level of glomerular immune deposits. 29114042
2019-06-15 12:21:00 These data suggest that increased plasma levels of FHR-3, altering the balance between factor H (FH) and FHR-3, likely impact the FH regulatory functions and contribute to the development of atypical hemolytic-uremic syndrome . 29740447

名称对应

Type IDs
Synonymous CFHL3, DOWN16, FHR-3, FHR3, HLF4
Gene
UniProtKB-ID: FHR3_HUMAN
UniprotKB: Q02985
UniParc: UPI00017A7715, UPI000012A73C
EMBL: BC058009, X68679, AK298459, AL049741
Ensembl: ENSG00000116785
KO: hsa:10878
Nucleutide sequences
EMBL-CDS: CAA48639.1, BAG60672.1, AAH58009.1
Ensembl_TRS: ENST00000367425, ENST00000391985
Protein sequencees
Ensembl_PRO: ENSP00000356395, ENSP00000375845
RefSeq: NP_066303.2, NP_001160096.1
Others
UniRef100: UniRef100_Q02985
UniRef90: UniRef90_Q02985
UniRef50: UniRef50_Q02985
UniGene: Hs.709217
CCDS: CCDS30958.1, CCDS53453.1

全选

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