| Type | Description |
|---|---|
| Definition | hematopoietic cell signal transducer |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:07:00 | NKG2D-DAP10 signaling recruits EVL to the cytotoxic synapse to generate F-actin and promote NK cell cytotoxicity. | 31235500 |
| 2016-09-10 11:22:00 | These results suggest that NKG2D-DAP10 endocytosis represents a means to decrease cell surface receptor abundance, as well as to control signaling outcome in cytotoxic lymphocytes. | 26508790 |
| 2014-12-20 10:47:00 | findings indicate that the functional interaction between and DAP10 coordinately regulates S100A8/A9-mediated survival and/or apoptotic response of keratinocytes | 25002577 |
| 2012-07-14 10:33:00 | TGF-beta1 may reduce the expression of NKG2D/DAP10 and 2B4/SAPin patients with hepatitis B. | 22438812 |
| 2012-01-14 11:59:00 | HMBOX1 negatively regulates the expression of NKG2D and the activation of the NKG2D/DAP10 signaling pathway in NK cells. | 21706044 |
| Type | IDs |
|---|---|
| Synonymous | DAP10, KAP10, PIK3AP |
| Gene |
UniProtKB-ID:
HCST_HUMAN
UniprotKB:
Q9UBK5
UniParc:
UPI000003597D,
UPI000006E074
EMBL:
AF122904,
AF072844,
AF172929,
AY359058,
BC035931,
BC046348,
AF285447,
BC065224,
AF072845,
AL050163
Ensembl:
ENSG00000126264
KO:
hsa:10870
|
| Nucleutide sequences |
EMBL-CDS:
AAD50293.1,
AAQ89417.1,
CAB43303.2,
AAD46987.1,
AAD46986.1,
AAH65224.1,
AAH46348.1,
AAD47911.1,
AAG29425.1,
AAH35931.1
Gene_ORFName:
UNQ587/PRO1157
Ensembl_TRS:
ENST00000437550,
ENST00000246551
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000400516,
ENSP00000246551
RefSeq:
NP_001007470.1,
XP_016881682.1,
NP_055081.1
|
| Others |
UniRef100:
UniRef100_Q9UBK5
UniRef90:
UniRef90_Q9UBK5
UniRef50:
UniRef50_Q9UBK5
UniGene:
Hs.117339
CCDS:
CCDS32998.1,
CCDS46057.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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