| Type | Description |
|---|---|
| Definition | COP9 signalosome subunit 8 |
| Date | Results | Publications |
|---|---|---|
| 2016-02-20 10:44:00 | CSN8/CSN promotes the ubiquitination and degradation of misfolded proteins and protects against cardiac proteotoxicity, and cullin-RING ligases participate in degradation of cytosolic misfolded proteins. | 26383969 |
| 2014-02-08 10:47:00 | Csn8 exerts profound impacts on hepatic ubiquitin-proteasome system function and is critical to the stability of the pro-apoptotic protein Bim. | 23840878 |
| 2013-11-23 10:35:00 | CSN8/COP9 signalosome regulates both proteasome-mediated proteolysis and the autophagic-lysosomal pathway, critical to the removal of oxidized proteins in the heart. | 23873473 |
| 2013-09-28 11:29:00 | Data indicate that a decreased level of Csn8 accelerated cell growth and shortened G1 duration. | 23689509 |
| 2012-01-07 11:34:00 | Likely through regulating the expression of Rab7, Csn8/CSN plays a critical role in autophagosome maturation in myocardium. | 21986281 |
| Type | IDs |
|---|---|
| Synonymous | 9430009J09Rik, AA408242, Csn8, Sgn8 |
| Gene |
UniProtKB-ID:
CSN8_MOUSE
UniprotKB:
Q8VBV7
UniParc:
UPI0000023E92
EMBL:
BC021488,
AF482000,
BC017690,
AK088323,
AK090013,
BC024421,
AK145899,
AK079111,
AK079522,
AK162502,
AF502144
Ensembl:
ENSMUSG00000034432
KO:
mmu:108679
|
| Nucleutide sequences |
EMBL-CDS:
AAL89689.1,
BAC37543.1,
BAE36948.1,
BAE26735.1,
AAH24421.1,
BAC41045.1,
AAH21488.1,
BAC40281.1,
AAH17690.1,
BAC37670.1,
AAP13731.1
Ensembl_TRS:
ENSMUST00000036153
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035884
RefSeq:
XP_006529127.1,
NP_598566.3
|
| Others |
UniRef100:
UniRef100_Q8VBV7
UniRef90:
UniRef90_Q8VBV7
UniRef50:
UniRef50_Q99627
UniGene:
Mm.119177
CCDS:
CCDS15153.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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