| Type | Description |
|---|---|
| Definition | cytochrome P450 family 46 subfamily A member 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-27 13:05:00 | Polymorphism within the CYP46A1 gene is a positive risk factor for type 2 diabetes mellitus. | 28206854 |
| 2018-12-22 12:13:00 | the APOEepsilon4 alleles were significantly higher in patients with Alzheimer's disease (AD) and there was a potential synergistic interaction between the CYP46A1 C allele and APOEepsilon4 allele in AD. | 29516283 |
| 2017-08-26 12:48:00 | Data suggest that CYP46A1, the enzyme responsible for the majority of cholesterol elimination from the brain, exhibits activation by neurotransmitters, L-glutamate, L-aspartate, gamma-aminobutyric acid, and acetylcholine; L-glutamate-induced CYP46A1 activation may be of physiological relevance. | 28642370 |
| 2017-07-29 10:58:00 | CYP46A1 rs4900442 genetic polymorphism was associated with increased risk of Alzheimer disease in the Chinese population, but no evidences were detected in Caucasian population. | 27026489 |
| 2017-03-25 11:48:00 | Findings of this study suggest that CYP46A1 gene and PPARgamma2 gene polymorphisms can be a predictive marker for early identification of population at risk of primary open angle glaucoma (POAG). | 27162448 |
| Type | IDs |
|---|---|
| Synonymous | CP46, CYP46 |
| Gene |
UniProtKB-ID:
CP46A_HUMAN
UniprotKB:
Q9Y6A2
UniParc:
UPI00000717EA,
UPI00017A730F,
UPI00001281DC
EMBL:
AL136000,
BC022539,
AK090886,
AK295216,
AF094480,
AL160313
Ensembl:
ENSG00000036530
KO:
hsa:10858
|
| Nucleutide sequences |
EMBL-CDS:
BAG58210.1,
AAD41244.1,
BAC03539.1,
AAH22539.1
Ensembl_TRS:
ENST00000380228,
ENST00000261835
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369577,
ENSP00000261835
RefSeq:
XP_016876422.1,
XP_011534666.1,
XP_011534667.1,
NP_006659.1,
XP_005267331.1
|
| Others |
UniRef100:
UniRef100_Q9Y6A2
UniRef90:
UniRef90_Q9Y6A2
UniRef50:
UniRef50_Q9Y6A2
UniGene:
Hs.25121
CCDS:
CCDS9954.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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