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10847 SRCAP

10847

SRCAP

Snf2 related CREBBP activator protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition Snf2 related CREBBP activator protein

研究结论

Date Results Publications
2019-10-05 12:25:00 cryo-EM structure of human SRCAP complex 30337683
2018-10-06 10:30:00 Data show that PCI domain-containing protein 2 (Pcid2) controls lymphoid lineage commitment through the regulation of Snf2-related CREBBP activator protein (SRCAP) remodelling activity. 29138493
2017-08-26 11:07:00 Alterative hypotheses to explain how the Srcap truncating mutations lead to the onset of Floating-Harbor syndrome are presented. 27208210
2015-07-04 16:19:00 Data confirm a mutational hot spot in the final exon of SRCAP in the majority of Floating-Harbor syndrome patients but also show that exon 33 of this gene can be affected. 25433523
2015-05-30 10:23:00 This study implicates the human SRCAP chromatin remodeling complex as a novel regulator of DNA damage responses that orchestrates proper signaling and repair of DSBs in the context of chromatin. 25176633

名称对应

Type IDs
Synonymous DOMO1, EAF1, FLHS, SWR1
Gene
UniProtKB-ID: SRCAP_HUMAN
UniprotKB: Q6ZRS2
UniParc: UPI0000EE7D89, UPI000059D368, UPI000059D367
EMBL: AK128030, AF143946, AB002307, AC093249, AC106886, BC159099
Ensembl: ENSG00000080603
KO: hsa:10847
Nucleutide sequences
EMBL-CDS: AAD39760.1, BAC87237.1, AAI59100.1, BAA20768.2
Ensembl_TRS: ENST00000262518
Protein sequencees
Ensembl_PRO: ENSP00000262518
RefSeq: NP_006653.2
Others
UniRef100: UniRef100_Q6ZRS2
UniRef90: UniRef90_Q6ZRS2
UniRef50: UniRef50_Q6ZRS2
UniGene: Hs.620916
CCDS: CCDS10689.2

全选

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研究热度

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