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1084 CEACAM3

1084

CEACAM3

carcinoembryonic antigen related cell adhesion molecule 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition carcinoembryonic antigen related cell adhesion molecule 3

研究结论

Date Results Publications
2020-12-26 13:12:00 CEACAM3 decreases asthma exacerbations and modulates respiratory syncytial virus latent infection in children. 32606071
2020-03-07 10:43:00 Amino acid alterations found in CEACAM3 translate into characteristic binding patterns for bacterial adhesins. One such amino acid residue is F62 in human and chimp CEACAM3, which is critical for binding the OMP P1 adhesin of Haemophilus aegyptius. Incorporation of the F62-containing motif into gorilla CEACAM3 results in a gain-of-function phenotype with regard to phagocytosis of H. aegyptius. 30744974
2019-09-14 10:06:00 High serum CEA expression is associated with systemic recurrence in colorectal cancer. 30852955
2018-08-04 12:14:00 the findings reveal an integration of the specific innate immune receptor CEACAM3 into the network of more conventional pattern recognition receptors, providing a mechanism by which the innate immune system can unleash its response to a relentless pathogen. 28886618
2018-01-27 11:08:00 Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1, CEACAM3, CEACAM5 or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA into host cells. 27748756

名称对应

Type IDs
Synonymous CD66D, CEA, CGM1, W264, W282
Gene
UniProtKB-ID: CEAM3_HUMAN
UniprotKB: P40198
UniParc: UPI0000140487, UPI000013C7E7, UPI000013CB39
EMBL: L00692, CH471126, D90277, L00693, BC106728, D90278, AC022516
Ensembl: ENSG00000170956
KO: hsa:1084
Nucleutide sequences
EMBL-CDS: AAA51970.1, EAW57063.1, BAA14321.1, AAA51969.1, BAA14322.1, EAW57062.1, AAI06729.1
Ensembl_TRS: ENST00000630848, ENST00000344550, ENST00000357396, ENST00000415495
Protein sequencees
Ensembl_PRO: ENSP00000485920, ENSP00000349971, ENSP00000411641, ENSP00000341725
RefSeq: NP_001264092.1, NP_001806.2
Others
UniRef100: UniRef100_P40198
UniRef90: UniRef90_P40198
UniRef50: UniRef50_P13688-7
UniGene: Hs.11
CCDS: CCDS12586.2, CCDS62685.1

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