| Type | Description |
|---|---|
| Definition | N-ethylmaleimide sensitive fusion protein attachment protein alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:12:00 | Pleiotropic effects of alpha-SNAP M105I mutation on oocyte biology: ultrastructural and cellular changes that adversely affect female fertility in mice. | 31758001 |
| 2019-06-29 11:07:00 | results showed that alpha-SNAP protein is highly expressed in granulosa cells and its expression is modulated by gonadotropin stimuli. | 28924180 |
| 2018-02-24 11:43:00 | alpha-SNAP is a crucial component of Orai1 channels, and its depletion disrupts the functional assembly of Orai1 multimers. Here the authors show that alpha-SNAP hypomorph, hydrocephalus with hopping gait, Napa(hyh/hyh) mice harbor significant defects in CD4 T cell gene expression and Foxp3 regulatory T cell (Treg) differentiation. | 28492364 |
| 2017-06-24 11:15:00 | Furthermore, alphaSNAP-deficient mutant animals displayed reduced formation of lysozyme granules in small intestinal crypts and decreased expression of lysozyme and defensins in the intestinal mucosa, which is indicative of defects in Paneth cell differentiation. By contrast, development of Goblet cells, enteroendocrine cells, and assembly of enterocyte apical junctions was not altered in hyh mutant mice. Our data reve... | 28359759 |
| 2013-06-22 11:39:00 | AMPK associates with alpha-SNAP, an adapter that enables disassembly of cis-SNARE complexes formed during membrane fusion. | 23463002 |
| Type | IDs |
|---|---|
| Synonymous | 1500039N14Rik, AW209189, RA81, SNAP-alpha, SNAPA, SNARE, a-SNAP, hyh |
| Gene |
UniProtKB-ID:
SNAA_MOUSE
UniprotKB:
Q9DB05
UniParc:
UPI00000040B4
EMBL:
AK136689,
BC004804,
AK050623,
AK005372,
AK171998
Ensembl:
ENSMUSG00000006024
KO:
mmu:108124
|
| Nucleutide sequences |
EMBL-CDS:
AAH04804.1,
BAB23981.1,
BAE23100.1,
BAC34348.1,
BAE42767.1
Ensembl_TRS:
ENSMUST00000006181
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006181
RefSeq:
NP_080174.1,
XP_030097834.1,
XP_030097835.1
|
| Others |
UniRef100:
UniRef100_Q9DB05
UniRef90:
UniRef90_P54920
UniRef50:
UniRef50_P54920
UniGene:
Mm.104540
CCDS:
CCDS20843.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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