| Type | Description |
|---|---|
| Definition | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:04:00 | These findings unveil distinct roles of duplicated tandem exon-derived U2AF1 isoforms in the regulation of the transcriptome and suggest U2AF1a-driven 5'-UTR alternative splicing as a molecular mechanism of mTOR-regulated translational control. | 31504847 |
| 2017-08-19 11:58:00 | The U2AF35(S34F) mutation alters interaction with CFIm59, leading to increased use of a distal cleavage and polyadenylation site in the ATG7 pre-mRNA, decreasing levels of ATG7 protein and defective autophagy, ultimately leading to transformation. | 27184077 |
| 2015-12-05 11:32:00 | data support the impact of genes from the Abcg1-U2af1 region as modifiers of Tc1-dependent memory and locomotor phenotypes in Tc1 mouse model of Down syndrome. | 25706610 |
| 2015-07-25 10:27:00 | findings support the hypothesis that mutant U2AF1 alters downstream gene isoform expression, thereby contributing to abnormal hematopoiesis in patients with MDS | 25965570 |
| 2010-02-15 11:13:00 | this study establishes definitely the contribution of the Abcg1-U2af1 orthologous region to the DS etiology and suggests new modulatory pathways for learning and memory. | 19783846 |
| Type | IDs |
|---|---|
| Synonymous | 2010107D16Rik |
| Gene |
UniProtKB-ID:
U2AF1_MOUSE,
G3UW94_MOUSE,
Q14C24_MOUSE
UniprotKB:
Q9D883,
G3UW94,
Q14C24
UniParc:
UPI0000434DB2,
UPI00000041C2
EMBL:
AK088979,
BC115480,
BC002184,
AK012849,
AC090881,
BC115479,
AK008332,
AK150872
Ensembl:
ENSMUSG00000061613
KO:
mmu:108121
|
| Nucleutide sequences |
EMBL-CDS:
BAC40683.1,
AAH02184.1,
BAB28511.1,
BAB25609.1,
BAE29923.1,
AAI15481.1,
AAI15480.1
Ensembl_TRS:
ENSMUST00000014684,
ENSMUST00000166526
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000014684,
ENSMUSP00000129864
RefSeq:
NP_001157241.1,
XP_006523535.1,
NP_001344836.1,
NP_077149.2,
XP_030105304.1
|
| Others |
UniRef100:
UniRef100_Q9D883,
UniRef100_G3UW94
UniRef90:
UniRef90_Q01081
UniRef50:
UniRef50_Q01081
UniGene:
Mm.379289
CCDS:
CCDS28611.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员