| Type | Description |
|---|---|
| Definition | brain-specific angiogenesis inhibitor 1-associated protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:53:00 | Disruption of Robo2-Baiap2 integrated signaling drives cystic disease. | 31534052 |
| 2020-09-26 13:01:00 | Superresolution microscopy reveals distinct localisation of full length IRSp53 and its I-BAR domain protein within filopodia. | 30792430 |
| 2018-10-20 11:37:00 | double knockout of IRSp53 and its closest family member, IRTKS, resulted in exacerbated placental abnormalities, particularly in spongiotrophoblast differentiation and development, giving rise to complete embryonic lethality. | 28067313 |
| 2013-12-21 11:23:00 | CDC42 activation inhibits this activity and promotes IRSp53-dependent recruitment and clustering of VASP to drive actin assembly. | 24076653 |
| 2013-09-28 11:56:00 | VASP physically interacted with IRSp53 in NIH-Src cells and was essential for podosome formation. | 23555988 |
| Type | IDs |
|---|---|
| Synonymous | IRSp53, R75030 |
| Gene |
UniProtKB-ID:
BAIP2_MOUSE,
Q3UKP6_MOUSE,
B1AZ46_MOUSE
UniprotKB:
Q8BKX1,
Q3UKP6,
B1AZ46
UniParc:
UPI00001E6BAC,
UPI0000002689,
UPI00000E6F51,
UPI000024DCD6,
UPI0000002688
EMBL:
AF390179,
AL953913,
AF390178,
AK145924,
AK049469,
AL929234,
BC016411,
BC006620,
AB105196
Ensembl:
ENSMUSG00000025372
KO:
mmu:108100
|
| Nucleutide sequences |
EMBL-CDS:
AAK81838.1,
BAC65241.1,
AAK68153.1,
AAH06620.1,
AAH16411.1,
BAC33764.1,
BAC65242.1,
BAE26755.1
Ensembl_TRS:
ENSMUST00000075180,
ENSMUST00000106231,
ENSMUST00000103021,
ENSMUST00000026436,
ENSMUST00000106233
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000074674,
ENSMUSP00000099310,
ENSMUSP00000026436,
ENSMUSP00000101838,
ENSMUSP00000101840
RefSeq:
NP_001032844.2,
XP_036012114.1,
XP_006532032.1,
NP_570932.2,
XP_006532031.1,
XP_006532030.1,
XP_006532029.1,
NP_001032843.1
|
| Others |
UniRef100:
UniRef100_Q8BKX1,
UniRef100_Q3UKP6,
UniRef100_B1AZ46
UniRef90:
UniRef90_Q3UKP6,
UniRef90_Q8BKX1
UniRef50:
UniRef50_Q9UQB8
UniGene:
Mm.197534
CCDS:
CCDS25724.1,
CCDS25723.1,
CCDS25722.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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