| Type | Description |
|---|---|
| Definition | latent transforming growth factor beta binding protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:29:00 | an AMPK-LTBP4 axis in inflammatory macrophages controls the production of TGF-beta1, which is further activated by and acts on fibroblastic cells, leading to fibrosis in Duchenne muscular dystrophy. | 30463013 |
| 2018-11-10 11:35:00 | These data suggest that LTBP-2 and -4 have critical overlapping functions in forming the robust structure of microfibrils in vitro and in vivo. | 28252045 |
| 2018-01-06 11:15:00 | Ltbp4 regulates Pdgfrb expression via TGFbeta-dependent modulation of Nrf2 transcription factor function. | 27645114 |
| 2017-12-09 11:23:00 | These data clearly establish a functional link between Ltbp-4L and fibulin-4 as a crucial molecular requirement for survival and elastogenesis in mice. | 27585882 |
| 2017-11-18 10:56:00 | Anxa6 and Ltbp4 isoforms modify the extent of damage in acute muscle injury in an additive fashion, and the severe isoform of Ltbp4, characteristic of the DBA/2J genetic background, correlated with upregulation of Slug and Snail, and downregulation of Anxa1 and Anxa6. | 29065150 |
| Type | IDs |
|---|---|
| Synonymous | 2310046A13Rik |
| Gene |
UniProtKB-ID:
LTBP4_MOUSE,
Q3UGU1_MOUSE
UniprotKB:
Q8K4G1,
Q3UGU1
UniParc:
UPI000163A143,
UPI00005AC6CD,
UPI0000D62941,
UPI000217CB42
EMBL:
AK147753,
BC059016,
AC157561,
AF410798,
AF410799
Ensembl:
ENSMUSG00000040488
KO:
mmu:108075
|
| Nucleutide sequences |
EMBL-CDS:
AAN04661.1,
AAN04662.1,
AAH59016.1,
BAE28116.1
Ensembl_TRS:
ENSMUST00000121175,
ENSMUST00000038618
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113674,
ENSMUSP00000037536
RefSeq:
NP_001297607.1,
XP_030097832.1,
XP_006539521.1,
XP_036008456.1,
NP_001107021.1,
XP_006539520.1,
NP_783572.2
|
| Others |
UniRef100:
UniRef100_Q8K4G1,
UniRef100_Q3UGU1
UniRef90:
UniRef90_Q3UGU1,
UniRef90_Q8K4G1
UniRef50:
UniRef50_Q8K4G1,
UniRef50_A0A1S3GGZ2
UniGene:
Mm.272251
CCDS:
CCDS52158.1,
CCDS21017.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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