| Type | Description |
|---|---|
| Definition | glutamate receptor, metabotropic 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:50:00 | Metabotropic glutamate receptor subtype 7 controls maternal care, maternal motivation and maternal aggression in mice. | 31793148 |
| 2020-06-27 12:29:00 | A transsynaptic interaction between Elfn1 and mGluR7 constitutively reduces initial release probability onto mouse cortical SOM neurons. Elfn1 produces glutamate-independent activation of mGluR7 via presynaptic clustering, resulting in a divergence from the canonical "autoreceptor" role of Type III mGluRs, and substantially altering synaptic pharmacology. | 30940718 |
| 2019-12-14 12:12:00 | mGlu7 is not functionally increased in mice overexpressing MeCP2 and that neither genetic nor pharmacological reduction of mGlu7 activity impacts phenotypes in a mouse model of MeCP2 duplication syndrome. | 29227625 |
| 2019-10-19 10:18:00 | We found a significant reduction of testosterone levels in mGluR7 knockout (KO) mice. Social investigating behaviour of intact mGluR7 KO mice also differed from that of wild-type mice; e.g. the KO mice showing less frequent anogenital sniffing and more frequent grooming behaviour. Further, castrated mGluR7 KO mice have smaller seminal vesicles than those of castrated wild-type mice, although intact mice were no different. | 29377390 |
| 2019-04-06 12:11:00 | Altered mGlu7 expression was found in brain regions associated with fear extinction in two different mouse strains which differ in their fear extinction behavior. | 30215216 |
| Type | IDs |
|---|---|
| Synonymous | 6330570A01Rik, BB176677, C030018L03, E130018M02Rik, Gpr1g, Gprc1g, SMN2, Tg(SMN2)89Ahmb, mGluR7 |
| Gene |
UniProtKB-ID:
GRM7_MOUSE,
G5E8D5_MOUSE
UniprotKB:
Q68ED2,
G5E8D5
UniParc:
UPI00021CF7DB,
UPI0000419FEB
EMBL:
AC132394,
AC125046,
AC142264,
AC114643,
AC121894,
AC165365,
AC169984,
BC080315,
AC169981
Ensembl:
ENSMUSG00000056755
KO:
mmu:108073
|
| Nucleutide sequences |
EMBL-CDS:
AAH80315.1
Ensembl_TRS:
ENSMUST00000172951,
ENSMUST00000071076
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000133957,
ENSMUSP00000064404
RefSeq:
XP_006505364.1,
XP_006505363.1,
NP_796302.2,
XP_006505359.1,
XP_006505365.1,
XP_017176787.1,
XP_006505361.1,
NP_001333569.1
|
| Others |
UniRef100:
UniRef100_G5E8D5,
UniRef100_Q68ED2
UniRef90:
UniRef90_P35400,
UniRef90_Q5RDQ8
UniRef50:
UniRef50_Q5RDQ8,
UniRef50_P35400
UniGene:
Mm.240881
CCDS:
CCDS39587.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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