例如:"NBL1", "4681", "drought"
收藏
108072 Grm6

108072

Grm6

glutamate receptor, metabotropic 6

protein-coding

Mus musculus

基因描述

Type Description
Definition glutamate receptor, metabotropic 6

研究结论

Date Results Publications
2020-07-11 11:00:00 Mislocalization of mutant mGluR6 is not normalized by reducing the total mGluR6. 32025181
2018-04-28 10:41:00 Laminar size and structure in missense Grm6(nob8) retina were comparable to control. The Grm6(nob8) phenotype is distinguished from other Grm6 mutants that carry a null allele by a reduced but not absent electroretinograph b-wave, decreased but present expression of mGluR6 at retinal depolarizing bipolar cells (DBCs) dendritic tips, and mislocalization of mGluR6 to DBC somas. In p.Met66Leu mutant mGluR6 is trafficked less 28490646
2017-11-18 13:46:00 Study suggests that the mGluR6 macromolecular complex is connected to the presynaptic rod terminal via a protein chain that includes the matrix-associated proteins. When a component of the macromolecular chain is missing, the chain may fall apart and loosen the dendritic tip adherence within the invagination. 27037829
2016-05-07 10:23:00 These results indicate that Grm6 nob7 is a new model of the complete form of congenital stationary night blindness. 26241901
2015-01-10 14:17:00 The mGluR6-KO phenotype showed negative effects on ribbon synapse formation. 24801622

名称对应

Type IDs
Synonymous BC021919, Gm3, Gprc1f, mGluR6, nerg1, nob2, nob3, nob4
Gene
UniProtKB-ID: GRM6_MOUSE, A7MD55_MOUSE, Q8CFQ7_MOUSE
UniprotKB: Q5NCH9, A7MD55, Q8CFQ7
UniParc: UPI0000027BB9, UPI000024D854, UPI00015C0106
EMBL: BC041684, AL627215, BC152480
Ensembl: ENSMUSG00000000617
KO: mmu:108072
Nucleutide sequences
EMBL-CDS: AAI52481.1, AAH41684.1
Ensembl_TRS: ENSMUST00000171427, ENSMUST00000000631
Protein sequencees
Ensembl_PRO: ENSMUSP00000000631, ENSMUSP00000130728
RefSeq: NP_775548.2, XP_006532027.1, XP_036012112.1, XP_017169707.1
Others
UniRef100: UniRef100_Q5NCH9, UniRef100_Q8CFQ7, UniRef100_A7MD55
UniRef90: UniRef90_Q8CFQ7, UniRef90_A7MD55, UniRef90_Q5NCH9
UniRef50: UniRef50_A0A0G2KZP1, UniRef50_O15303, UniRef50_G1NCH9
UniGene: Mm.134265
CCDS: CCDS48785.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员