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108069 Grm3

108069

Grm3

glutamate receptor, metabotropic 3

protein-coding

Mus musculus

基因描述

Type Description
Definition glutamate receptor, metabotropic 3

研究结论

Date Results Publications
2020-06-27 10:32:00 hese findings suggest that mGlu3 receptors have a strong impact on the development of cortical GABAergic transmission and cortical neural synchronization mechanisms corroborating the concept that genetic variants of mGlu3 receptors may predispose to psychiatric disorders. 31665922
2020-03-21 10:53:00 Grm3(-/-) mice did not have a stress-resilient phenotype. 30939596
2019-01-19 12:15:00 Loss of Nogo-A, encoded by the schizophrenia risk gene Rtn4, reduces mGlu3 expression and causes hyperexcitability in hippocampal CA3 circuits 30040841
2018-02-03 11:20:00 the activation of mGluR3 up-regulates the membrane expression of TWIK-1 that in turn enhances NH4(+) uptake in astrocytes. 26553349
2017-06-03 12:15:00 These studies provide a foundation for future research seeking to parse out the roles of mGlu2 from mGlu3, paving the way for better understanding of how these receptors regulate activity in the brain. 27818290

名称对应

Type IDs
Synonymous 0710001G23Rik, Gprc1c, mGlu3, mGluR3
Gene
UniProtKB-ID: GRM3_MOUSE
UniprotKB: Q9QYS2
UniParc: UPI0000020DAC
EMBL: BC111891, BC113170, AF170698, AF170697, AF170701, AF170700, AF170699
Ensembl: ENSMUSG00000003974
KO: mmu:108069
Nucleutide sequences
EMBL-CDS: AAI11892.1, AAF06741.1, AAI13171.1
Ensembl_TRS: ENSMUST00000004076
Protein sequencees
Ensembl_PRO: ENSMUSP00000004076
RefSeq: XP_036020611.1, XP_036020612.1, NP_862898.1, XP_036020613.1
Others
UniRef100: UniRef100_Q9QYS2
UniRef90: UniRef90_P31422
UniRef50: UniRef50_P31422
UniGene: Mm.318966
CCDS: CCDS19090.1

全选

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研究热度

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