| Type | Description |
|---|---|
| Definition | glutamate receptor, metabotropic 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:53:00 | Grm2(-/-) mice had a stress-resilient phenotype. | 30939596 |
| 2018-07-14 10:11:00 | Here we show that glutamate signals through metabotropic glutamate receptor 2 (mGluR2) to induce Erk phosphorylation in SC. mGluR2-elicited Erk phosphorylation requires ErbB2/3 receptor tyrosine kinase phosphorylation to limit the signaling cascade that promotes phosphorylation of Erk, but not Akt. | 27432639 |
| 2018-05-12 10:21:00 | activation of mGlu2 receptors is detrimental in the post-ischemic phase, and support the use of mGlu2 receptor antagonists in the experimental treatment of brain ischemia. | 28821279 |
| 2017-09-02 13:39:00 | mGlu2 activation exerts effects on striatal physiology that extend beyond modulation of corticostriatal synapses, and has the potential to influence cognition and striatum-related disorders via inhibition of thalamus-derived glutamate and dopamine release. | 28159646 |
| 2017-06-03 12:15:00 | These studies provide a foundation for future research seeking to parse out the roles of mGlu2 from mGlu3, paving the way for better understanding of how these receptors regulate activity in the brain. | 27818290 |
| Type | IDs |
|---|---|
| Synonymous | 4930441L02Rik, Gprc1b, mGluR2, mGluR7 |
| Gene |
UniProtKB-ID:
GRM2_MOUSE
UniprotKB:
Q14BI2
UniParc:
UPI00000220FB
EMBL:
BC115866,
AC152452
Ensembl:
ENSMUSG00000023192
KO:
mmu:108068
|
| Nucleutide sequences |
EMBL-CDS:
AAI15867.1
Ensembl_TRS:
ENSMUST00000023959
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023959
RefSeq:
NP_001153825.1
|
| Others |
UniRef100:
UniRef100_Q14BI2
UniRef90:
UniRef90_Q14416
UniRef50:
UniRef50_Q14416
UniGene:
Mm.410822,
Mm.424639
CCDS:
CCDS52914.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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