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108052 Slc14a1

108052

Slc14a1

solute carrier family 14 (urea transporter), member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 14 (urea transporter), member 1

研究结论

Date Results Publications
2020-08-01 15:19:00 results suggest that the depletion of SLC14alpha1 gene in mice may contribute to the HS-induced abnormality of sodium transportation in the CSF 32387413
2017-11-04 11:37:00 functional deficiency of all UTs caused a urea-selective urine-concentrating defect with little physiological abnormality in extrarenal organs. 27914708
2017-05-27 10:44:00 We conclude that transgenic expression of UT-A1 restores basal urea permeability to the level in wild-type mice but does not restore vasopressin-stimulated levels of urea permeability. This information suggests that transgenic expression of UT-A1 alone in mice lacking UT-A1 and UT-A3 is sufficient to restore urine-concentrating ability 26407594
2017-05-13 18:43:00 These results demonstrate that the descending thin limb (DTL) of the intermediate loop is composed of type I epithelium and expresses both UT-A2. The functional role of the DTL of the intermediate loop may be distinct from the short or long loops. 27091563
2015-05-02 12:28:00 Studies indicate that urea transporter Slc14a1 UT-B is an indispensable transporter involved in maintaining physiological functions in different tissues. 25298344

名称对应

Type IDs
Synonymous 2610507K20Rik, 3021401A05Rik, UT-B, Utb1
Gene
UniProtKB-ID: UT1_MOUSE
UniprotKB: Q8VHL0
UniParc: UPI00001EC3E6, UPI0000001B71
EMBL: BC100570, AK012066, AJ420967, BC086673, CH466528, AF448798, BC058594, AK041979, AK153891
Ensembl: ENSMUSG00000116373, ENSMUSG00000059336
KO: mmu:108052
Nucleutide sequences
EMBL-CDS: AAH58594.2, BAC31119.1, AAL47138.1, AAH86673.1, CAD12807.1, BAB28004.1, BAE32238.1, AAI00571.2, EDL09438.1, EDL09437.1
Ensembl_TRS: ENSMUST00000160639, ENSMUST00000091813, ENSMUST00000229465, ENSMUST00000160292, ENSMUST00000229681, ENSMUST00000230088
Protein sequencees
Ensembl_PRO: ENSMUSP00000155208, ENSMUSP00000125367, ENSMUSP00000125114, ENSMUSP00000155358, ENSMUSP00000089421, ENSMUSP00000154891
RefSeq: NP_001164482.1, NP_001164481.1, NP_082398.1
Others
UniRef100: UniRef100_Q8VHL0
UniRef90: UniRef90_Q8VHL0
UniRef50: UniRef50_Q8VHL0
UniGene: Mm.33832
CCDS: CCDS50330.1, CCDS29360.1

全选

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