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107934 Celsr3

107934

Celsr3

cadherin, EGF LAG seven-pass G-type receptor 3

protein-coding

Mus musculus

基因描述

Type Description
Definition cadherin, EGF LAG seven-pass G-type receptor 3

研究结论

Date Results Publications
2018-05-05 10:13:00 Celsr3 is dispensable for the patterning of central dorsal root ganglion projections, but it regulates for the fine mapping of sensory fibers in the gray matter, which is important for somatosensory processing. 28754314
2018-04-14 11:16:00 The Celsr3-mediated signaling pathway responds to the inhibitory function of Wnt5a in glutamatergic synapse formation. We also revealed the opposing roles of Wnt-regulated planar cell polarity components, Celsr3 and Vangl2, in glutamatergic synapse formation. 28057866
2018-01-20 11:45:00 Results suggest that Celsr3 and Fzd3 orchestrate the formation of a scaffold of pioneer neurons and their axons during embryogenesis. This scaffold extends from prethalamus to ventral telencephalon and subcortex, and steers reciprocal corticothalamic fibers. 27170656
2016-07-30 10:39:00 Celsr3 and Fzd3 enable immature neurons to respond to Wnt7, upregulate Jag1 and thereby facilitate feedback signals that tune the timing of neural progenitor cell fate decisions via Notch activation. 26939553
2014-12-06 11:19:00 Our results provide evidence that the Celsr3-Fzd3 pathway interacts with EphA-ephrinA reverse signaling to guide motor axons in the hindlimb. 25108913

名称对应

Type IDs
Synonymous Adgrc3, Fmi1, flamingo, mKIAA0812
Gene
UniProtKB-ID: CELR3_MOUSE
UniprotKB: Q91ZI0
UniParc: UPI0000D8B305
EMBL: AF427498, AF188752, AC168054
Ensembl: ENSMUSG00000107269, ENSMUSG00000023473
KO: mmu:107934
Nucleutide sequences
EMBL-CDS: AAL25099.1, AAG17057.1
Ensembl_TRS: ENSMUST00000201574, ENSMUST00000024238
Protein sequencees
Ensembl_PRO: ENSMUSP00000024238, ENSMUSP00000144254
RefSeq: XP_006511685.1, NP_001346501.1, NP_001346502.1, XP_006511688.1, NP_536685.2, XP_006511686.1, XP_006511689.1
Others
UniRef100: UniRef100_Q91ZI0
UniRef90: UniRef90_Q91ZI0
UniRef50: UniRef50_Q91ZI0
UniGene: Mm.39945

全选

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研究热度

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