| Type | Description |
|---|---|
| Definition | IQ motif containing GTPase activating protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:24:00 | Circular RNA sequencing indicates circ-IQGAP2 and circ-ZC3H6 as noninvasive biomarkers of primary Sjogren's syndrome. | 32250392 |
| 2020-12-05 12:58:00 | IQGAP2 Inhibits Migration and Invasion of Gastric via Elevating SHIP2 Phosphatase Activity. | 32183047 |
| 2019-01-12 10:47:00 | Data suggest that CDC42 binding to Ex-domain of IQGAP2 releases Ex-domain at C-terminal region of GRD2 domain, facilitating IQGAP2 dimerization; this promotes allosteric changes in ras GTPase-activating protein binding site providing binding site for second CDC42; RAC1 binds only to apo-IQGAP2. (IQGAP2 = IQ motif containing GTPase activating protein-2; CDC42 = GTP-binding protein CDC42; RAC1 = Rac family small GTPase-1) | 29358323 |
| 2017-11-11 10:09:00 | IQGAP2 expression correlated positively with survivability, on the contrary, IQGAP3 expression levels correlated inversely with survivability | 29073199 |
| 2017-10-07 11:23:00 | The structural basis for Cdc42-induced dimerization of IQGAP1 and IQGAP2 has been uncovered. | 27524202 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IQGA2_HUMAN,
B7Z7X2_HUMAN,
Q59HA3_HUMAN,
B7Z7U6_HUMAN
UniprotKB:
Q13576,
B7Z7X2,
Q59HA3,
B7Z7U6
UniParc:
UPI00019152CB,
UPI000020CB2C,
UPI00015E072C,
UPI00004F6A94,
UPI0001915269,
UPI0001D3B41C
EMBL:
AC026706,
AK302510,
U51903,
AB208856,
AK291066,
AK302599,
AC025188,
AY351902,
AK303054,
AC112173,
AC093251,
AC026725
Ensembl:
ENSG00000145703
KO:
hsa:10788
|
| Nucleutide sequences |
EMBL-CDS:
BAH13890.1,
BAF83755.1,
AAQ81291.1,
AAB37765.1,
BAH13758.1,
BAD92093.1,
BAH13732.1
Ensembl_TRS:
ENST00000396234,
ENST00000502745,
ENST00000274364
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379535,
ENSP00000274364,
ENSP00000426027
RefSeq:
NP_001272389.2,
NP_006624.3,
NP_001272390.2,
XP_005248471.1,
XP_024310105.1,
XP_005248467.1,
XP_016864449.1,
NP_001272391.2,
XP_024310104.1,
XP_011541410.1
|
| Others |
UniRef100:
UniRef100_A0A024RAJ8,
UniRef100_B7Z7U6,
UniRef100_Q13576,
UniRef100_B7Z7X2
UniRef90:
UniRef90_B7Z7X2,
UniRef90_Q13576
UniRef50:
UniRef50_Q13576,
UniRef50_B7Z7X2
UniGene:
Hs.291030
CCDS:
CCDS68897.1,
CCDS34188.1,
CCDS68898.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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