| Type | Description |
|---|---|
| Definition | NCK associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:30:00 | NCKAP1 Disruptive Variants Lead to a Neurodevelopmental Disorder with Core Features of Autism. | 33157009 |
| 2020-05-23 10:19:00 | NCKAP1 is a tumor suppress gene that modulates the cell cycle of HCC cell lines by targeting Rb1/p53 regulation. | 31068575 |
| 2019-07-27 11:21:00 | Results demonstrate the importance and functional regulation of the HSP90-NAP1 protein complex in cancer metastatic signaling. | 30867003 |
| 2017-07-29 10:21:00 | we show that stapled peptides targeting the interface between NCKAP1 and CYFIP1 destabilize the WASF3 complex... thereby suppressing invasion and metastasis of breast cancer cells. | 27432794 |
| 2017-05-27 12:09:00 | We identify three mosaic missense and likely-gene disrupting mutations in genes previously implicated in ASD (KMT2C, NCKAP1, and MYH10) in probands but none in siblings. We find a strong ascertainment bias for mosaic mutations in probands relative to their unaffected siblings | 27632392 |
| Type | IDs |
|---|---|
| Synonymous | HEM2, NAP1, NAP125, p125Nap1 |
| Gene |
UniProtKB-ID:
NCKP1_HUMAN
UniprotKB:
Q9Y2A7
UniParc:
UPI0000000DED,
UPI00001693F2
EMBL:
BC015025,
AC108514,
AK292914,
AC064871,
AB011159,
BT007033,
AB014509
Ensembl:
ENSG00000061676
KO:
hsa:10787
|
| Nucleutide sequences |
EMBL-CDS:
BAF85603.1,
AAY24196.1,
AAH15025.1,
AAX93118.1,
BAA25513.2,
BAA77295.1,
AAP35681.1
Ensembl_TRS:
ENST00000361354,
ENST00000360982
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354251,
ENSP00000355348
RefSeq:
XP_006712264.1,
NP_995314.1,
XP_006712263.1,
NP_038464.1
|
| Others |
UniRef100:
UniRef100_Q9Y2A7
UniRef90:
UniRef90_P28660
UniRef50:
UniRef50_P28660
UniGene:
Hs.603732,
Hs.708541
CCDS:
CCDS2288.1,
CCDS2287.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员