| Type | Description |
|---|---|
| Definition | solute carrier family 17 member 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 11:35:00 | Study used rs548987 of SLC17A3 as a candidate variant of ischemic stroke and performed association analysis in a Chinese population; although rs548987 failed to show significant association with total ischemic stroke and large vessel disease subtype, the C allele of rs548987 showed significant association with small vessel disease subtype of ischemic stroke (OR=0.68, p=0.004). | 27772792 |
| 2012-02-18 10:35:00 | hNPT4 (SLC17A3) mediated time- and concentration-dependent uptake of OTxA (K(m): 802.8 microM) in a pH- and voltage-sensitive manner. | 21778665 |
| 2011-09-10 10:42:00 | variants carrying SNP V257F, G279R, or P378L exhibited reduced transport of para-aminohippurate, bumetanide, estrone and urate; SNPs may contribute to inter-individual differences in disposition of anionic drugs and certain endogenous organic anions | 21282933 |
| 2010-12-11 10:53:00 | Genetic variants within SLC2A9,ABCG2 and SLC17A3 are associated with uric acid levels | 20053405 |
| 2010-12-04 10:56:00 | a model of urate secretion in the renal tubular cell, where intracellular urate taken up via OAT1 and/or OAT3 from the blood exits from the cell into the lumen via hNPT4. | 20810651 |
| Type | IDs |
|---|---|
| Synonymous | GOUT4, NPT4, UAQTL4 |
| Gene |
UniProtKB-ID:
NPT4_HUMAN,
A0A024QZX7_HUMAN
UniprotKB:
O00476,
A0A024QZX7
UniParc:
UPI000006FCFB,
UPI0001536779
EMBL:
CH471087,
BC017952,
AK298271,
U90545,
AL138726
Ensembl:
ENSG00000124564
KO:
hsa:10786
|
| Nucleutide sequences |
EMBL-CDS:
AAH17952.1,
EAW55495.1,
AAB53423.1,
BAH12747.1,
EAW55497.1
Gene_ORFName:
hCG_19117
Ensembl_TRS:
ENST00000360657,
ENST00000397060,
ENST00000361703
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380250,
ENSP00000355307,
ENSP00000353873
RefSeq:
NP_001091956.1,
NP_006623.2
|
| Others |
UniRef100:
UniRef100_O00476
UniRef90:
UniRef90_O00476
UniRef50:
UniRef50_O00476
UniGene:
Hs.327179
CCDS:
CCDS4566.2,
CCDS47385.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 27772792 |
J Neurol Sci Shouqing Huang , Lianhua Yin , Yihui Xu , Chunyan Zou , Lidian Chen |
2016-11-15 | - |
| 24954895 |
Am J Hum Genet Jeannette Simino , Gang Shi , Joshua C Bis , Daniel I Chasman , Georg B Ehret , Xiangjun Gu , Xiuqing Guo , Shih-Jen Hwang , Eric Sijbrands , Albert V Smith , Germaine C Verwoert , Jennifer L Bragg-Gresham , Gemma Cadby , Peng Chen , Ching-Yu Cheng , Tanguy Corre , Rudolf A de Boer , Anuj Goel , Toby Johnson , Chiea-Chuen Khor , LifeLines Cohort Study , Carla LluÃs-Ganella , Jian'an Luan , Leo-Pekka Lyytikäinen , Ilja M Nolte , Xueling Sim , Siim Sõber , Peter J van der Most , Niek Verweij , Jing Hua Zhao , Najaf Amin , Eric Boerwinkle , Claude Bouchard , Abbas Dehghan , Gudny Eiriksdottir , Roberto Elosua , Oscar H Franco , Christian Gieger , Tamara B Harris , Serge Hercberg , Albert Hofman , Alan L James , Andrew D Johnson , Mika Kähönen , Kay-Tee Khaw , Zoltan Kutalik , Martin G Larson , Lenore J Launer , Guo Li , Jianjun Liu , Kiang Liu , Alanna C Morrison , Gerjan Navis , Rick Twee-Hee Ong , George J Papanicolau , Brenda W Penninx , Bruce M Psaty , Leslie J Raffel , Olli T Raitakari , Kenneth Rice , Fernando Rivadeneira , Lynda M Rose , Serena Sanna , Robert A Scott , David S Siscovick , Ronald P Stolk , Andre G Uitterlinden , Dhananjay Vaidya , Melanie M van der Klauw , Ramachandran S Vasan , Eranga Nishanthie Vithana , Uwe Völker , Henry Völzke , Hugh Watkins , Terri L Young , Tin Aung , Murielle Bochud , Martin Farrall , Catharina A Hartman , Maris Laan , Edward G Lakatta , Terho Lehtimäki , Ruth J F Loos , Gavin Lucas , Pierre Meneton , Lyle J Palmer , Rainer Rettig , Harold Snieder , E Shyong Tai , Yik-Ying Teo , Pim van der Harst , Nicholas J Wareham , Cisca Wijmenga , Tien Yin Wong , Myriam Fornage , Vilmundur Gudnason , Daniel Levy , Walter Palmas , Paul M Ridker , Jerome I Rotter , Cornelia M van Duijn , Jacqueline C M Witteman , Aravinda Chakravarti , Dabeeru C Rao |
2014-07-03 | - |
| 24816252 |
An atlas of genetic influences on human blood metabolites. Nat. Genet. So-Youn Shin , Eric B Fauman , Ann-Kristin Petersen , Jan Krumsiek , Rita Santos , Jie Huang , Matthias Arnold , Idil Erte , Vincenzo Forgetta , Tsun-Po Yang , Klaudia Walter , Cristina Menni , Lu Chen , Louella Vasquez , Ana M Valdes , Craig L Hyde , Vicky Wang , Daniel Ziemek , Phoebe Roberts , Li Xi , Elin Grundberg , Multiple Tissue Human Expression Resource (MuTHER) Consortium , Melanie Waldenberger , J Brent Richards , Robert P Mohney , Michael V Milburn , Sally L John , Jeff Trimmer , Fabian J Theis , John P Overington , Karsten Suhre , M Julia Brosnan , Christian Gieger , Gabi Kastenmüller , Tim D Spector , Nicole Soranzo |
2014-06-01 | - |
| 23824729 |
Am. J. Clin. Nutr. Joyce B J van Meurs , Guillaume Pare , Stephen M Schwartz , Aditi Hazra , Toshiko Tanaka , Sita H Vermeulen , Ioana Cotlarciuc , Xin Yuan , Anders Mälarstig , Stefania Bandinelli , Joshua C Bis , Henk Blom , Morris J Brown , Constance Chen , Yii-Der Chen , Robert J Clarke , Abbas Dehghan , Jeanette Erdmann , Luigi Ferrucci , Anders Hamsten , Albert Hofman , David J Hunter , Anuj Goel , Andrew D Johnson , Sekar Kathiresan , Ellen Kampman , Douglas P Kiel , Lambertus A L M Kiemeney , John C Chambers , Peter Kraft , Jan Lindemans , Barbara McKnight , Christopher P Nelson , Christopher J O'Donnell , Bruce M Psaty , Paul M Ridker , Fernando Rivadeneira , Lynda M Rose , Udo Seedorf , David S Siscovick , Heribert Schunkert , Jacob Selhub , Per M Ueland , Peter Vollenweider , Gérard Waeber , Dawn M Waterworth , Hugh Watkins , Jacqueline C M Witteman , Martin den Heijer , Paul Jacques , Andre G Uitterlinden , Jaspal S Kooner , Dan J Rader , Muredach P Reilly , Vincent Mooser , Daniel I Chasman , Nilesh J Samani , Kourosh R Ahmadi |
2013-09-01 | - |
| 23263486 |
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet Anna Köttgen , Eva Albrecht , Alexander Teumer , Veronique Vitart , Jan Krumsiek , Claudia Hundertmark , Giorgio Pistis , Daniela Ruggiero , Conall M O'Seaghdha , Toomas Haller , Qiong Yang , Toshiko Tanaka , Andrew D Johnson , Zoltán Kutalik , Albert V Smith , Julia Shi , Maksim Struchalin , Rita P S Middelberg , Morris J Brown , Angelo L Gaffo , Nicola Pirastu , Guo Li , Caroline Hayward , Tatijana Zemunik , Jennifer Huffman , Loic Yengo , Jing Hua Zhao , Ayse Demirkan , Mary F Feitosa , Xuan Liu , Giovanni Malerba , Lorna M Lopez , Pim van der Harst , Xinzhong Li , Marcus E Kleber , Andrew A Hicks , Ilja M Nolte , Asa Johansson , Federico Murgia , Sarah H Wild , Stephan J L Bakker , John F Peden , Abbas Dehghan , Maristella Steri , Albert Tenesa , Vasiliki Lagou , Perttu Salo , Massimo Mangino , Lynda M Rose , Terho Lehtimäki , Owen M Woodward , Yukinori Okada , Adrienne Tin , Christian Müller , Christopher Oldmeadow , Margus Putku , Darina Czamara , Peter Kraft , Laura Frogheri , Gian Andri Thun , Anne Grotevendt , Gauti Kjartan Gislason , Tamara B Harris , Lenore J Launer , Patrick McArdle , Alan R Shuldiner , Eric Boerwinkle , Josef Coresh , Helena Schmidt , Michael Schallert , Nicholas G Martin , Grant W Montgomery , Michiaki Kubo , Yusuke Nakamura , Toshihiro Tanaka , Patricia B Munroe , Nilesh J Samani , David R Jacobs , Kiang Liu , Pio D'Adamo , Sheila Ulivi , Jerome I Rotter , Bruce M Psaty , Peter Vollenweider , Gerard Waeber , Susan Campbell , Olivier Devuyst , Pau Navarro , Ivana Kolcic , Nicholas Hastie , Beverley Balkau , Philippe Froguel , Tõnu Esko , Andres Salumets , Kay Tee Khaw , Claudia Langenberg , Nicholas J Wareham , Aaron Isaacs , Aldi Kraja , Qunyuan Zhang , Philipp S Wild , Rodney J Scott , Elizabeth G Holliday , Elin Org , Margus Viigimaa , Stefania Bandinelli , Jeffrey E Metter , Antonio Lupo , Elisabetta Trabetti , Rossella Sorice , Angela Döring , Eva Lattka , Konstantin Strauch , Fabian Theis , Melanie Waldenberger , H-Erich Wichmann , Gail Davies , Alan J Gow , Marcel Bruinenberg , LifeLines Cohort Study , Ronald P Stolk , Jaspal S Kooner , Weihua Zhang , Bernhard R Winkelmann , Bernhard O Boehm , Susanne Lucae , Brenda W Penninx , Johannes H Smit , Gary Curhan , Poorva Mudgal , Robert M Plenge , Laura Portas , Ivana Persico , Mirna Kirin , James F Wilson , Irene Mateo Leach , Wiek H van Gilst , Anuj Goel , Halit Ongen , Albert Hofman , Fernando Rivadeneira , Andre G Uitterlinden , Medea Imboden , Arnold von Eckardstein , Francesco Cucca , Ramaiah Nagaraja , Maria Grazia Piras , Matthias Nauck , Claudia Schurmann , Kathrin Budde , Florian Ernst , Susan M Farrington , Evropi Theodoratou , Inga Prokopenko , Michael Stumvoll , Antti Jula , Markus Perola , Veikko Salomaa , So-Youn Shin , Tim D Spector , Cinzia Sala , Paul M Ridker , Mika Kähönen , Jorma Viikari , Christian Hengstenberg , Christopher P Nelson , CARDIoGRAM Consortium , DIAGRAM Consortium , ICBP Consortium , MAGIC Consortium , James F Meschia , Michael A Nalls , Pankaj Sharma , Andrew B Singleton , Naoyuki Kamatani , Tanja Zeller , Michel Burnier , John Attia , Maris Laan , Norman Klopp , Hans L Hillege , Stefan Kloiber , Hyon Choi , Mario Pirastu , Silvia Tore , Nicole M Probst-Hensch , Henry Völzke , Vilmundur Gudnason , Afshin Parsa , Reinhold Schmidt , John B Whitfield , Myriam Fornage , Paolo Gasparini , David S Siscovick , Ozren Polašek , Harry Campbell , Igor Rudan , Nabila Bouatia-Naji , Andres Metspalu , Ruth J F Loos , Cornelia M van Duijn , Ingrid B Borecki , Luigi Ferrucci , Giovanni Gambaro , Ian J Deary , Bruce H R Wolffenbuttel , John C Chambers , Winfried März , Peter P Pramstaller , Harold Snieder , Ulf Gyllensten , Alan F Wright , Gerjan Navis , Hugh Watkins , Jacqueline C M Witteman , Serena Sanna , Sabine Schipf , Malcolm G Dunlop , Anke Tönjes , Samuli Ripatti , Nicole Soranzo , Daniela Toniolo , Daniel I Chasman , Olli Raitakari , W H Linda Kao , Marina Ciullo , Caroline S Fox , Mark Caulfield , Murielle Bochud , Christian Gieger |
2013-02-01 | - |
| 23222517 |
Seventy-five genetic loci influencing the human red blood cell. Nature Pim van der Harst , Weihua Zhang , Irene Mateo Leach , Augusto Rendon , Niek Verweij , Joban Sehmi , Dirk S Paul , Ulrich Elling , Hooman Allayee , Xinzhong Li , Aparna Radhakrishnan , Sian-Tsung Tan , Katrin Voss , Christian X Weichenberger , Cornelis A Albers , Abtehale Al-Hussani , Folkert W Asselbergs , Marina Ciullo , Fabrice Danjou , Christian Dina , Tõnu Esko , David M Evans , Lude Franke , Martin Gögele , Jaana Hartiala , Micha Hersch , Hilma Holm , Jouke-Jan Hottenga , Stavroula Kanoni , Marcus E Kleber , Vasiliki Lagou , Claudia Langenberg , Lorna M Lopez , Leo-Pekka Lyytikäinen , Olle Melander , Federico Murgia , Ilja M Nolte , Paul F O'Reilly , Sandosh Padmanabhan , Afshin Parsa , Nicola Pirastu , Eleonora Porcu , Laura Portas , Inga Prokopenko , Janina S Ried , So-Youn Shin , Clara S Tang , Alexander Teumer , Michela Traglia , Sheila Ulivi , Harm-Jan Westra , Jian Yang , Jing Hua Zhao , Franco Anni , Abdel Abdellaoui , Antony Attwood , Beverley Balkau , Stefania Bandinelli , François Bastardot , Beben Benyamin , Bernhard O Boehm , William O Cookson , Debashish Das , Paul I W de Bakker , Rudolf A de Boer , Eco J C de Geus , Marleen H de Moor , Maria Dimitriou , Francisco S Domingues , Angela Döring , Gunnar Engström , Gudmundur Ingi Eyjolfsson , Luigi Ferrucci , Krista Fischer , Renzo Galanello , Stephen F Garner , Bernd Genser , Quince D Gibson , Giorgia Girotto , Daniel Fannar Gudbjartsson , Sarah E Harris , Anna-Liisa Hartikainen , Claire E Hastie , Bo Hedblad , Thomas Illig , Jennifer Jolley , Mika Kähönen , Ido P Kema , John P Kemp , Liming Liang , Heather Lloyd-Jones , Ruth J F Loos , Stuart Meacham , Sarah E Medland , Christa Meisinger , Yasin Memari , Evelin Mihailov , Kathy Miller , Miriam F Moffatt , Matthias Nauck , Maria Novatchkova , Teresa Nutile , Isleifur Olafsson , Pall T Onundarson , Debora Parracciani , Brenda W Penninx , Lucia Perseu , Antonio Piga , Giorgio Pistis , Anneli Pouta , Ursula Puc , Olli Raitakari , Susan M Ring , Antonietta Robino , Daniela Ruggiero , Aimo Ruokonen , Aude Saint-Pierre , Cinzia Sala , Andres Salumets , Jennifer Sambrook , Hein Schepers , Carsten Oliver Schmidt , Herman H W Silljé , Rob Sladek , Johannes H Smit , John M Starr , Jonathan Stephens , Patrick Sulem , Toshiko Tanaka , Unnur Thorsteinsdottir , Vinicius Tragante , Wiek H van Gilst , L Joost van Pelt , Dirk J van Veldhuisen , Uwe Völker , John B Whitfield , Gonneke Willemsen , Bernhard R Winkelmann , Gerald Wirnsberger , Ale Algra , Francesco Cucca , Adamo Pio d'Adamo , John Danesh , Ian J Deary , Anna F Dominiczak , Paul Elliott , Paolo Fortina , Philippe Froguel , Paolo Gasparini , Andreas Greinacher , Stanley L Hazen , Marjo-Riitta Jarvelin , Kay Tee Khaw , Terho Lehtimäki , Winfried Maerz , Nicholas G Martin , Andres Metspalu , Braxton D Mitchell , Grant W Montgomery , Carmel Moore , Gerjan Navis , Mario Pirastu , Peter P Pramstaller , Ramiro Ramirez-Solis , Eric Schadt , James Scott , Alan R Shuldiner , George Davey Smith , J Gustav Smith , Harold Snieder , Rossella Sorice , Tim D Spector , Kari Stefansson , Michael Stumvoll , W H Wilson Tang , Daniela Toniolo , Anke Tönjes , Peter M Visscher , Peter Vollenweider , Nicholas J Wareham , Bruce H R Wolffenbuttel , Dorret I Boomsma , Jacques S Beckmann , George V Dedoussis , Panos Deloukas , Manuel A Ferreira , Serena Sanna , Manuela Uda , Andrew A Hicks , Josef Martin Penninger , Christian Gieger , Jaspal S Kooner , Willem H Ouwehand , Nicole Soranzo , John C Chambers |
2012-12-20 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21778665 |
A novel human organic anion transporter NPT4 mediates the transport of ochratoxin A. J. Pharmacol. Sci. Promsuk Jutabha , Naohiko Anzai , Keitaro Hayashi , Mariko Domae , Kohsuke Uchida , Hitoshi Endou , Hiroyuki Sakurai |
2011-01-01 | - |
| 21282933 |
Functional analysis of human sodium-phosphate transporter 4 (NPT4/SLC17A3) polymorphisms. J. Pharmacol. Sci. Promsuk Jutabha , Naohiko Anzai , Toru Kimura , Atsuo Taniguchi , Wako Urano , Hisashi Yamanaka , Hitoshi Endou , Hiroyuki Sakurai |
2011-01-01 | - |
| 20810651 |
J Biol Chem Promsuk Jutabha , Naohiko Anzai , Kenichiro Kitamura , Atsuo Taniguchi , Shuji Kaneko , Kunimasa Yan , Hideomi Yamada , Hidetaka Shimada , Toru Kimura , Tomohisa Katada , Toshiyuki Fukutomi , Kimio Tomita , Wako Urano , Hisashi Yamanaka , George Seki , Toshiro Fujita , Yoshinori Moriyama , Akira Yamada , Shunya Uchida , Michael F Wempe , Hitoshi Endou , Hiroyuki Sakurai |
2010-11-05 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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