| Type | Description |
|---|---|
| Definition | WD repeat domain 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 10:50:00 | WDR4 is an additional example of a gene that encodes a tRNA modifying enzyme and gives rise to Galloway-Mowat syndrome, if mutated | 30079490 |
| 2019-08-03 10:36:00 | We report here 2 sisters harboring compound heterozygous variants of WDR4. Their phenotype differs from that of the first 2 described patients: they both have a severe microcephaly but only one of the 2 sisters had a head circumference at birth below -2 SD, their intellectual deficiency is less severe, and they have a growth hormone deficiency and a partial hypogonadotropic hypogonadotropism | 28617965 |
| 2017-10-14 12:46:00 | WDR4 is an oncoprotein that negatively regulates PML via ubiquitination to promote lung cancer progression by fostering an immunosuppressive and prometastatic tumor microenvironment | 28691927 |
| 2016-07-16 11:29:00 | Combined autozygome/exome analysis revealed a novel missense mutation in WDR4 as the likely causal variant of Primordial dwarfism | 26416026 |
| 2016-06-11 10:52:00 | regulates FEN1's potential DNA cleavage threat near the site of replication | 26751069 |
| Type | IDs |
|---|---|
| Synonymous | TRM82, TRMT82 |
| Gene |
UniProtKB-ID:
WDR4_HUMAN
UniprotKB:
P57081
UniParc:
UPI000016039B,
UPI00019B2238,
UPI00000372F0
EMBL:
AK315008,
AB039887,
AP001629,
CH471079,
BC001074,
BC006341,
AJ243912,
AK298015,
AK056343,
AJ243913,
AK292923
Ensembl:
ENSG00000160193
KO:
hsa:10785
|
| Nucleutide sequences |
EMBL-CDS:
BAG37500.1,
AAH06341.1,
CAB93144.1,
EAX09529.1,
CAB93145.1,
AAH01074.1,
BAG60319.1,
BAG51684.1,
BAB13726.1,
BAF85612.1,
EAX09528.1
Ensembl_TRS:
ENST00000398208,
ENST00000330317
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000328671,
ENSP00000381266
RefSeq:
NP_001247405.1,
NP_001247404.1,
NP_001247403.1,
XP_024307818.1,
XP_016883753.1,
NP_387510.1,
XP_024307815.1,
XP_016883752.1,
NP_001247406.1,
XP_024307816.1,
XP_024307817.1,
XP_011527735.1,
NP_061139.2,
XP_016883751.1
|
| Others |
UniRef100:
UniRef100_P57081
UniRef90:
UniRef90_P57081
UniRef50:
UniRef50_P57081
UniGene:
Hs.248815,
Hs.711744
CCDS:
CCDS13691.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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