| Type | Description |
|---|---|
| Definition | adhesion G protein-coupled receptor B1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 12:48:00 | Rather, BAI1 associates with the Rho-GTPase regulatory protein Bcr late in development and stimulates its cryptic RhoA-GEF activity, which functions together with its Rac1-GAP activity to terminate dendritic arborization. | 31461398 |
| 2019-02-23 11:02:00 | Study demonstrated that an evolutionarily conserved fragment in the C-terminal cytoplasmic tail of BAI-aGPCRs is specifically recognized by the RBD-ARR-ELMO (RAE) supramodule of the ELMO family scaffolds. The crystal structures of ELMO2-RAE and its complex with BAI1 uncover the molecular basis of BAI/ELMO interactions. | 30604775 |
| 2016-10-29 11:26:00 | these findings suggest that BAI1 mediates the clearance of Gram-negative bacteria by stimulating both phagocytosis and NADPH oxidase activation, thereby coupling bacterial detection to the cellular microbicidal machinery. | 26838550 |
| 2016-10-01 10:04:00 | transgenic mice overexpressing BAI1 had fewer apoptotic cells, reduced inflammation, and attenuated disease. Boosting BAI1-mediated uptake by intestinal epithelial cells was important in attenuating inflammation. | 27037190 |
| 2015-07-04 11:00:00 | BAI1(-) mice have deficits in hippocampus-dependent spatial learning and memory, enhanced long-term potentiation, impaired long-term depression, and postsynaptic density thinning. BAI1 stops PSD-95 polyubiquitination/degradation via interaction with MDM2. | 25751059 |
| Type | IDs |
|---|---|
| Synonymous | B830018M07Rik, Bai1, R75078, mKIAA4089 |
| Gene |
UniProtKB-ID:
AGRB1_MOUSE
UniprotKB:
Q3UHD1
UniParc:
UPI00005AC660
EMBL:
AK147456,
AK147459,
AK147494,
AK147607,
AY168408
Ensembl:
ENSMUSG00000034730
KO:
mmu:107831
|
| Nucleutide sequences |
EMBL-CDS:
BAE28021.1,
BAE27923.1,
BAE27926.1,
AAN86966.1,
BAE27949.1
Ensembl_TRS:
ENSMUST00000042035
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046097
RefSeq:
XP_006520332.1,
XP_011243705.1,
XP_011243707.1,
XP_030104131.1,
XP_011243708.1,
NP_001346688.1,
XP_006520333.1,
XP_006520334.1,
XP_011243706.1,
XP_030104128.1,
NP_778156.2
|
| Others |
UniRef100:
UniRef100_Q3UHD1
UniRef90:
UniRef90_Q3UHD1
UniRef50:
UniRef50_O14514
UniGene:
Mm.43133
CCDS:
CCDS70635.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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