| Type | Description |
|---|---|
| Definition | jumonji domain containing 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:10:00 | JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. | 32048991 |
| 2019-12-14 10:47:00 | Knocking down JMJD6 reduces neuroblastoma cell proliferation and survival in vitro and tumor progression in mice. | 31346162 |
| 2017-09-30 14:12:00 | TEC-specific deletion of Jmjd6 exacerbates development of autoimmune diabetes in a mouse model, which express both ovalbumin (OVA) under the control of the rat insulin gene promoter and OT-I T cell receptor specific for OVA peptide bound to major histocompatibility complex class I K(b) molecules. | 28546003 |
| 2016-05-14 10:14:00 | Although Jmjd6 deficiency does not affect abundance of Aire transcript, the intron 2 of Aire gene is not effectively spliced out in the absence of Jmjd6, resulting in reduction of mature Aire protein and spontaneous multi-organ autoimmunity in mice. | 26531897 |
| 2015-12-26 11:32:00 | The results indicate dual roles for JMJD6 in promoting adipogenic gene expression program by post-transcriptional regulation of C/EBPbeta and C/EBPdelta and direct transcriptional activation of Ppargamma2 and Cebpalpha during adipocyte differentiation. | 26117538 |
| Type | IDs |
|---|---|
| Synonymous | 5730436I23Rik, D11Ertd195e, PSR, PtdSerR, Ptdsr, mKIAA0585 |
| Gene |
UniProtKB-ID:
JMJD6_MOUSE
UniprotKB:
Q9ERI5
UniParc:
UPI0000026881,
UPI00015F45ED
EMBL:
AK122317,
AL645542,
AF304118,
BC056629
Ensembl:
ENSMUSG00000056962
KO:
mmu:107817
|
| Nucleutide sequences |
EMBL-CDS:
AAH56629.1,
BAC65599.1,
AAG27719.1
Ensembl_TRS:
ENSMUST00000047616
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047570
RefSeq:
NP_001350292.1,
NP_203971.2
|
| Others |
UniRef100:
UniRef100_Q9ERI5
UniRef90:
UniRef90_Q9ERI5
UniRef50:
UniRef50_Q6NYC1
UniGene:
Mm.481684
CCDS:
CCDS25678.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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