| Type | Description |
|---|---|
| Definition | Scm polycomb group protein like 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:43:00 | Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition. | 32895557 |
| 2020-04-04 10:40:00 | These results suggest that the rapid evolution of SCML2 is due to reproductive adaptation, which has promoted species-specific gene expression programs in spermatogenesis. | 30137219 |
| 2019-12-07 11:49:00 | SCML2 accumulates on pericentromeric heterochromatin (PCH) in male germ cells, where it suppresses PRC1-mediated monoubiquitylation of histone H2A at Lysine 119 (H2AK119ub) and promotes deposition of PRC2-mediated H3K27me3 during meiosis. | 30097555 |
| 2018-08-18 10:05:00 | SCML2-dependent H3K27me3 in the male germline prepares the expression of developmental regulator and somatic genes in embryonic development. | 29686098 |
| 2018-07-21 10:40:00 | RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 for gene activation on sex chromosomes. | 29462142 |
| Type | IDs |
|---|---|
| Synonymous | 4932420G07Rik |
| Gene |
UniProtKB-ID:
I6L9E4_MOUSE,
B1AVB5_MOUSE,
B1AVB4_MOUSE,
Q8BYC8_MOUSE
UniprotKB:
I6L9E4,
B1AVB5,
B1AVB4,
Q8BYC8
UniParc:
UPI0000EE05C2,
UPI0000225E31,
UPI00000EA572,
UPI0000EE05C3
EMBL:
AL672233,
BC056382,
AL670462,
AK040521
Ensembl:
ENSMUSG00000000037
KO:
mmu:107815
|
| Nucleutide sequences |
EMBL-CDS:
AAH56382.1,
BAC30615.1
Ensembl_TRS:
ENSMUST00000019101,
ENSMUST00000074802
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019101,
ENSMUSP00000074356
RefSeq:
XP_006528736.1,
NP_001277581.1,
NP_001277580.1,
XP_006528735.1,
XP_006528733.1
|
| Others |
UniRef100:
UniRef100_I6L9E4,
UniRef100_B1AVB5,
UniRef100_Q8BYC8,
UniRef100_B1AVB4
UniRef90:
UniRef90_B1AVB4,
UniRef90_B1AVB5
UniRef50:
UniRef50_B1AVB5,
UniRef50_B1AVB4
UniGene:
Mm.159173
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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