| Type | Description |
|---|---|
| Definition | Rap guanine nucleotide exchange factor (GEF) 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-03-18 10:53:00 | C3G is required in cortical neurons for both the specification of an axon and the initiation of radial migration by forming a leading process. | 27111087 |
| 2015-12-05 11:54:00 | results provide evidence that C3G plays an important role in myogenic differentiation by coordinating cell cycle exit, actin dynamics and survival signaling. | 26133694 |
| 2013-03-09 12:18:00 | C3G regulates sympathetic preganglionic neuron migration by acting downstream in the reelin signaling pathway. | 22351125 |
| 2012-12-22 10:47:00 | Data indicate that chemical rescue of c-Src provided a tool to dissect the spatiotemporal mechanism of activation of the Rap1 guanine exchange factor, C3G, one of the identified potential c-Src substrates that plays a role in focal adhesion signaling. | 22499769 |
| 2011-06-18 10:51:00 | GEF and Dlx1/2 form part of a common signalling pathway during GABAergic neuronal development. | 20436929 |
| Type | IDs |
|---|---|
| Synonymous | 4932418O06Rik, C3G, Grf2 |
| Gene |
UniProtKB-ID:
Q8C5V7_MOUSE,
A0A5F8MPI9_MOUSE,
Q3UHC1_MOUSE,
Q3UGX8_MOUSE,
Q91ZZ2_MOUSE
UniprotKB:
Q8C5V7,
A0A5F8MPI9,
Q3UHC1,
Q3UGX8,
Q91ZZ2
UniParc:
UPI00005AC666,
UPI00000298C1,
UPI0003D71AE2,
UPI00000E9C01,
UPI00005AC6B9
EMBL:
AK147696,
AK147470,
AK077034,
AK147506,
AL845323,
AF348669,
AK147468
Ensembl:
ENSMUSG00000039844
KO:
mmu:107746
|
| Nucleutide sequences |
EMBL-CDS:
BAC36578.1,
BAE27936.1,
BAE27934.1,
BAE27960.1,
BAE28079.1,
AAK97373.1
Ensembl_TRS:
ENSMUST00000238899,
ENSMUST00000095087,
ENSMUST00000091146,
ENSMUST00000102872
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000158995,
ENSMUSP00000092703,
ENSMUSP00000088680,
ENSMUSP00000099936
RefSeq:
NP_001034176.1,
XP_030102343.1,
XP_030102347.1,
XP_036013192.1,
XP_006497649.1,
XP_030102345.1,
XP_030102344.1,
XP_006497655.1,
XP_030102348.1,
XP_036013181.1,
NP_001034175.1,
XP_036013191.1,
XP_036013170.1,
XP_006497653.1,
XP_006497646.1,
XP_006497650.1,
XP_036013173.1,
NP_001349631.1,
XP_030102342.1,
XP_006497648.1,
XP_006497652.1,
XP_036013197.1,
XP_030102341.1,
XP_006497647.1,
NP_473391.1,
XP_036013177.1,
XP_006497645.1
|
| Others |
UniRef100:
UniRef100_Q3UHC1,
UniRef100_Q91ZZ2,
UniRef100_A0A5F8MPI9,
UniRef100_Q3UGX8,
UniRef100_Q8C5V7
UniRef90:
UniRef90_Q3UGX8,
UniRef90_Q91ZZ2,
UniRef90_Q3UHC1
UniRef50:
UniRef50_Q13905,
UniRef50_Q91ZZ2
UniGene:
Mm.298274
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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