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10768 AHCYL1

10768

AHCYL1

adenosylhomocysteinase like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition adenosylhomocysteinase like 1

研究结论

Date Results Publications
2019-11-09 12:30:00 IRBIT controlled five phosphorylation sites in NBCe1-B that determined both the active conformation of the transporter and its regulation by Cl(-) 30377224
2019-08-10 12:36:00 in the group receiving postoperative adjuvant chemotherapy, a significant association was found between IRBIT expression and both overall and disease-free survival. IRBIT may be used as a useful predictive marker for chemotherapy. 31366495
2018-06-09 11:20:00 We investigated previously assumed interaction with AHCY-like-1 protein (AHCYL1), a paralog of AHCY. Indeed, significant interaction between both proteins exists. Additionally, silencing AHCYL1 leads to moderate inhibition of nuclear export of endogenous AHCY. 28647132
2018-01-20 10:08:00 We have validated the vectors and confirmed self-association of AHCY, AHCYL1, and galectin-3. In a high-throughput BiFC screen, we identified new AHCY interaction partners: galectin-3 and PUS7L. We also describe additional steps in protein interaction analysis, applied for AHCY-galectin-3 interaction 27455993
2017-11-04 12:39:00 These results suggest that by inhibiting Bcl2l10 activity and promoting contact between endoplasmic reticulum and mitochondria, IRBIT facilitates massive Ca(2+) transfer to mitochondria and promotes apoptosis. 27995898

名称对应

Type IDs
Synonymous DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA
Gene
UniProtKB-ID: SAHH2_HUMAN, A0A024R0A8_HUMAN
UniprotKB: O43865, A0A024R0A8
UniParc: UPI0000458B06, UPI00000022AC
EMBL: AL049954, BC007576, BC110896, BC065254, AK316110, AL772411, T19009, BC016942, BC010681, BK005417, AF315687, AU279527, BI460083, BK005418, GQ900917, AL036027, AK303690, BC095476, CH471122, U82761
Ensembl: ENSG00000168710
KO: hsa:10768
Nucleutide sequences
EMBL-CDS: AAC01960.1, AAL26869.1, CAH70966.1, AAI10897.2, DAA05762.1, BAH14481.1, CAB43223.2, CAH70965.1, BAG64680.1, AAH95476.2, EAW56426.1, AAH65254.2, AAH16942.3, AAH10681.3, DAA05763.1, AAH07576.3, ADO22434.1, EAW56425.1, EAW56427.1
Gene_ORFName: hCG_38162
Ensembl_TRS: ENST00000369799, ENST00000393614, ENST00000359172
Protein sequencees
Ensembl_PRO: ENSP00000352092, ENSP00000358814, ENSP00000377238
RefSeq: XP_011538837.1, NP_006612.2, NP_001229603.1, NP_001229602.1, NP_001229604.1, NP_001229605.1
Others
UniRef100: UniRef100_O43865
UniRef90: UniRef90_O43865
UniRef50: UniRef50_O43865
UniGene: Hs.743973
CCDS: CCDS55620.1, CCDS818.1

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