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107589 Mylk

107589

Mylk

myosin, light polypeptide kinase

protein-coding

Mus musculus

基因描述

Type Description
Definition myosin, light polypeptide kinase

研究结论

Date Results Publications
2021-03-13 13:24:00 Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE. 32772419
2020-07-18 10:29:00 It was concluded that MLCK is part of a multicomponent signaling pathway in both the cytoplasm and nucleus that includes much more than simple regulation of conventional nonmuscle myosins through myosin regulatory light chain phosphorylation. 31904282
2019-08-10 11:42:00 nmMLCK is a potential molecular target to counteract early stages of atherosclerosis, such as endothelial dysfunction, inflammation through its capacity to increase transendothelial migration of monocytes and, most importantly, through the reorganization of VAMP-dependent vesicles associated with the release of IL-6 in modeled obstructive sleep apnea. 29057883
2019-07-20 10:53:00 Report direct role for hnRNPA1 in MYLK alternative splicing in lung endothelial cells. 29077485
2019-05-11 10:54:00 a unique domain within the MLCK splice variant MLCK1 directs perijunctional actomyosin ring (PAMR) recruitment. 30936544

名称对应

Type IDs
Synonymous 9530072E15Rik, A930019C19Rik, AW489456, KRP, MLCK108, MLCK210, Mlck, nmMlck, smMLCK
Gene
UniProtKB-ID: B1B1A8_MOUSE
UniprotKB: B1B1A8
UniParc: UPI0000D63566
EMBL: CT010574, AC154813, BC150749, AC110166, BC145279
Ensembl: ENSMUSG00000022836
KO: mmu:107589
Nucleutide sequences
EMBL-CDS: AAI45280.1, AAI50750.1
Ensembl_TRS: ENSMUST00000023538
Protein sequencees
Ensembl_PRO: ENSMUSP00000023538
RefSeq: XP_017172338.1, XP_006521766.1, XP_006521765.1, NP_647461.3, XP_006521768.1
Others
UniRef100: UniRef100_B1B1A8
UniRef90: UniRef90_Q6PDN3
UniRef50: UniRef50_Q15746-4
UniGene: Mm.33360

全选

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研究热度

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