| Type | Description |
|---|---|
| Definition | leucine-rich repeat-containing G protein-coupled receptor 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | Lgr4 Deletion Delays the Hair Cycle and Inhibits the Activation of Hair Follicle Stem Cells. | 32035093 |
| 2020-05-16 11:43:00 | LGR4 is essential for mesoderm-derived tissue development and bone mesenchymal stem cell differentiation. | 30536377 |
| 2019-11-23 10:20:00 | Liver-specific knockdown of LGR4 renders liver more susceptible to acute injury | 30406697 |
| 2019-09-21 11:39:00 | blocking Rspo-Lgr4 signaling overcame Lewis lung carcinoma (LLC) resistance to anti-PD-1 therapy and improved the efficacy of PD-1 immunotherapy against B16F10 melanoma, indicating vital roles of Rspo-Lgr4 in host antitumor immunity and a potential therapeutic target in cancer immunotherapy. | 29967265 |
| 2019-01-12 11:26:00 | findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast cancer stem cell. | 29269400 |
| Type | IDs |
|---|---|
| Synonymous | 9130225G07, A330106J01Rik, A930009A08Rik, Gpr48 |
| Gene |
UniProtKB-ID:
LGR4_MOUSE,
Q8BZR7_MOUSE
UniprotKB:
A2ARI4,
Q8BZR7
UniParc:
UPI0000D778B8,
UPI00001E326D,
UPI00000EA3C0
EMBL:
BC056637,
AY255619,
AK044357,
BX294391,
AL845423,
AK033699,
AL928922
Ensembl:
ENSMUSG00000050199
KO:
mmu:107515
|
| Nucleutide sequences |
EMBL-CDS:
AAO85131.1,
AAH56637.1,
BAC31882.1,
BAC28434.1
Ensembl_TRS:
ENSMUST00000111037,
ENSMUST00000046548
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106666,
ENSMUSP00000047325
RefSeq:
NP_766259.2,
XP_036013142.1
|
| Others |
UniRef100:
UniRef100_A2ARI4
UniRef90:
UniRef90_A2ARI4
UniRef50:
UniRef50_A2ARI4
UniGene:
Mm.277351,
Mm.485992
CCDS:
CCDS38195.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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