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107477 Guca1b

107477

Guca1b

guanylate cyclase activator 1B

protein-coding

Mus musculus

基因描述

Type Description
Definition guanylate cyclase activator 1B

研究结论

Date Results Publications
2021-01-16 15:59:00 GCAP neuronal calcium sensor proteins mediate photoreceptor cell death in the rd3 mouse model of LCA12 congenital blindness by involving endoplasmic reticulum stress. 31980596
2019-01-26 12:40:00 conclude that, under normal physiological conditions, GCAP1 dominates the regulation of cGMP synthesis in mouse cones, but if its function becomes compromised, GCAP2 contributes to the regulation of phototransduction and light adaptation of cones 29549122
2015-05-30 12:14:00 The GCAP1 and GCAP2 binding site(s) overlaps within the kinase homology and/or dimerization domains of retinal GC1. 25616661
2015-02-14 12:47:00 This study identifies a new mechanism governing GCAP2 subcellular distribution in vivo, closely related to disease. 25058152
2013-05-04 10:47:00 Overexpression of guanylate cyclase activating protein 2 in rod photoreceptors in vivo leads to morphological changes at the synaptic ribbon. 22912773

名称对应

Type IDs
Synonymous BC018258, GCAP2
Gene
UniProtKB-ID: GUC1B_MOUSE, E9PWU1_MOUSE
UniprotKB: Q8VBV8, E9PWU1
UniParc: UPI00000221E2, UPI00001EB212
EMBL: BC018480, BC033358, BC034331, AC112683, BC033380, BC031367, BC029661, AK033052, BC018258, BC034595, BC031916, BC029017, BC033383
Ensembl: ENSMUSG00000116266, ENSMUSG00000023979
KO: mmu:107477
Nucleutide sequences
EMBL-CDS: BAC28139.1, AAH33358.1, AAH31916.1, AAH34331.1, AAH34595.1, AAH33380.1, AAH31367.1, AAH33383.1, AAH18480.1, AAH29017.1, AAH29661.1, AAH18258.1
Ensembl_TRS: ENSMUST00000024774, ENSMUST00000229925, ENSMUST00000145462
Protein sequencees
Ensembl_PRO: ENSMUSP00000155668, ENSMUSP00000024774, ENSMUSP00000126799
RefSeq: XP_036016150.1, NP_666191.1
Others
UniRef100: UniRef100_E9PWU1, UniRef100_Q8VBV8
UniRef90: UniRef90_Q8VBV8, UniRef90_E9PWU1
UniRef50: UniRef50_Q8VBV8
UniGene: Mm.59151
CCDS: CCDS28847.1

全选

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