| Type | Description |
|---|---|
| Definition | retinoic acid induced 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-25 12:17:00 | RAI2 is frequently methylated in colorectal cancer, and its expression is regulated by promoter region methylation. Methylation of RAI2 is an independent prognostic marker of poor survival. RAI2 suppresses CRC cell growth both in vitro and in vivo. RAI2 induces cell apoptosis and suppresses CRC cell migration and invasion. RAI2 may serve as a tumor suppressor by inhibiting the AKT signaling pathway in CRC. | 29796120 |
| 2018-06-02 11:47:00 | Here, we report a microdeletion of 170,6 Kb at Xp22.13 (17.733.948-17.904.576) (GRCh37/hg19).The microdeletion harbors the NHS, SCLML1, and RAI2 genes and results in a phenotype consistent with Nance-Horan syndromesyndrome and developmental delay. | 28464487 |
| 2016-06-04 11:54:00 | We specified the role of the RAI2 protein to function as a transcriptional regulator that controls the expression of several key regulators of breast epithelial integrity and cancer. | 25716347 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RAI2_HUMAN,
B2RBE9_HUMAN,
A0A024RBZ8_HUMAN,
B3KPD7_HUMAN
UniprotKB:
Q9Y5P3,
B2RBE9,
A0A024RBZ8,
B3KPD7
UniParc:
UPI00017507F5,
UPI00001330F1,
UPI00003718E0,
UPI000013CE19,
UPI0001AE6F9F
EMBL:
AF136587,
AK298873,
CH471074,
AK314631,
AK056214,
Z93242,
BC027937
Ensembl:
ENSG00000131831
KO:
hsa:10742
|
| Nucleutide sequences |
EMBL-CDS:
AAH27937.1,
AAD33688.1,
BAG60991.1,
BAG37196.1,
EAW98935.1,
EAW98933.1,
EAW98934.1,
BAG51649.1
Gene_ORFName:
hCG_1640698
Ensembl_TRS:
ENST00000415486,
ENST00000451717,
ENST00000545871,
ENST00000360011,
ENST00000331511
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000401323,
ENSP00000333456,
ENSP00000444210,
ENSP00000392578,
ENSP00000353106
RefSeq:
NP_001166214.2,
XP_006724523.1,
XP_011543741.1,
XP_011543743.1,
XP_011543742.1,
NP_001166203.2,
XP_006724522.1,
NP_068557.4,
NP_001166210.2
|
| Others |
UniRef100:
UniRef100_B2RBE9,
UniRef100_Q9Y5P3,
UniRef100_A0A024RBZ8,
UniRef100_B3KPD7
UniRef90:
UniRef90_Q9Y5P3-2,
UniRef90_Q9Y5P3
UniRef50:
UniRef50_Q9Y5P3
UniGene:
Hs.446680
CCDS:
CCDS14183.1,
CCDS55374.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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