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10738 RFPL3

10738

RFPL3

ret finger protein like 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition ret finger protein like 3

研究结论

Date Results Publications
2018-10-13 10:39:00 EGF significantly upregulated RFPL3 and hTERT protein levels in the nonsmall cell lung cancer cells. RFPL3 and hTERT proteins upregulation by EGF were attenuated by pretreatment with AG1478 and erlotinib. EGF promoted proliferation and inhibited apoptosis; PD98059 decreased RFPL3 and hTERT protein expression; and RFPL3 overexpression increased the expression of hTERT and related MEKpathway proteins 29749533
2016-08-20 10:10:00 RFPL3 and CBP have roles in upregulating hTERT activity and promoting lung cancer growth 26318425
2015-10-24 10:07:00 These results demonstrate that RFPL3 is an important cellular factor which promotes lung cancer growth by activating hTERT expression 25481043
2015-02-07 11:14:00 RFPL3 is a potential stimulator of human immunodeficiency virus, type 1 (HIV-1) preintegration complex integration. 25107902
2010-01-21 00:00:00 the human RFPL1,2,3 genes have a role in neocortex development 18656177

名称对应

Type IDs
Synonymous RNF120
Gene
UniProtKB-ID: RFPL3_HUMAN
UniprotKB: O75679
UniParc: UPI0000133803, UPI000013CC68
EMBL: AL021937, CR456564, BC069753, AJ010232, BC031689
Ensembl: ENSG00000128276
KO: hsa:10738
Nucleutide sequences
EMBL-CDS: CAG30450.1, AAH31689.1, AAH69753.2, CAA09046.1
Ensembl_TRS: ENST00000397468, ENST00000249007
Protein sequencees
Ensembl_PRO: ENSP00000380609, ENSP00000249007
RefSeq: XP_016884023.1, NP_001092005.1, NP_006595.1
Others
UniRef100: UniRef100_O75679
UniRef90: UniRef90_O75679
UniRef50: UniRef50_O75679
UniGene: Hs.558455
CCDS: CCDS13904.1, CCDS43011.1

全选

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研究热度

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