| Type | Description |
|---|---|
| Definition | SIX homeobox 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:36:00 | The six2 knockdown attenuated the stemness of Renal cell carcinoma (RCC) cells, which was evident by decreased spheroid formation ability and stemness marker (sox2 and nanog) expression. | 31420918 |
| 2020-05-02 10:56:00 | Elevated Six2 expression in hepatocellular carcinoma patients was associated with negative prognosis. Upregulated Six2 promoted tumor growth and facilitated HCC metastasis via TGF-beta/Smad signal pathway. | 31564506 |
| 2020-02-01 11:27:00 | Glomerular Six-2 deposits in renal biopsy should be validated in prospective series as a predictor of renal outcome in renal amyloidosis | 31343337 |
| 2019-12-14 10:47:00 | High Six2 expression is associated with Late-Stage Metastasis in triple-negative breast cancer. | 30606720 |
| 2019-12-07 10:46:00 | findings identify a NIK-SIX signalling axis that fine-tunes inflammatory gene expression programs under both physiological and pathological conditions | 30894749 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SIX2_HUMAN,
Q8TBA2_HUMAN
UniprotKB:
Q9NPC8,
Q8TBA2
UniParc:
UPI000007253B,
UPI00001359C0
EMBL:
AF332198,
BC024033,
AF323498,
AF136939,
AF332197,
BT020100,
AF136940,
AF332196
Ensembl:
ENSG00000170577
KO:
hsa:10736
|
| Nucleutide sequences |
EMBL-CDS:
AAK16583.1,
AAF69031.1,
AAK16582.1,
AAK06773.1,
AAK16581.1,
AAF69032.1,
AAV38903.1,
AAH24033.1
Ensembl_TRS:
ENST00000303077
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304502
RefSeq:
XP_005264157.1,
NP_058628.3
|
| Others |
UniRef100:
UniRef100_Q9NPC8,
UniRef100_Q8TBA2
UniRef90:
UniRef90_Q9NPC8
UniRef50:
UniRef50_Q9NPC8
UniGene:
Hs.101937
CCDS:
CCDS1822.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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