| Type | Description |
|---|---|
| Definition | polo like kinase 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | Non-mitotic functions of polo-like kinases in cancer cells. | 33171265 |
| 2021-02-20 13:33:00 | YLZ-F5, a novel polo-like kinase 4 inhibitor, inhibits human ovarian cancer cell growth by inducing apoptosis and mitotic defects. | 32519033 |
| 2021-01-30 13:02:00 | Polo-like kinase 4 correlates with greater tumor size, lymph node metastasis and confers poor survival in non-small cell lung cancer. | 31876063 |
| 2020-12-12 13:29:00 | TRIM37 controls cancer-specific vulnerability to PLK4 inhibition. | 32908304 |
| 2020-10-31 13:14:00 | A cis-eQTL genetic variant in PLK4 confers high risk of hepatocellular carcinoma. | 31489978 |
| Type | IDs |
|---|---|
| Synonymous | MCCRP2, SAK, STK18 |
| Gene |
UniProtKB-ID:
PLK4_HUMAN
UniprotKB:
O00444
UniParc:
UPI0000422B71,
UPI0001B30121,
UPI000007426E
EMBL:
AK302858,
Y13115,
AK314238,
AB006972,
BC036023,
AK303399
Ensembl:
ENSG00000142731
KO:
hsa:10733
|
| Nucleutide sequences |
EMBL-CDS:
AAH36023.1,
BAB69958.1,
BAG36907.1,
BAH13823.1,
BAH13953.1,
CAA73575.1
Ensembl_TRS:
ENST00000270861,
ENST00000514379,
ENST00000513090
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000427554,
ENSP00000270861,
ENSP00000423582
RefSeq:
NP_001177730.1,
NP_055079.3,
XP_016863152.1,
NP_001177728.1,
XP_005262758.1,
XP_016863151.1
|
| Others |
UniRef100:
UniRef100_O00444
UniRef90:
UniRef90_O00444
UniRef50:
UniRef50_O00444
UniGene:
Hs.172052
CCDS:
CCDS54803.1,
CCDS54804.1,
CCDS3735.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员