| Type | Description |
|---|---|
| Definition | YME1 like 1 ATPase |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | Examination of the Role of Mg(2+) in the Mechanism of Nucleotide Binding to the Monomeric YME1L AAA+ Domain. | 33155794 |
| 2020-04-11 10:13:00 | identify the mTORC1-LIPIN1-YME1L axis as a post-translational regulator of mitochondrial proteostasis at the interface between metabolism and mitochondrial dynamics | 31695197 |
| 2019-12-14 11:27:00 | in the absence of ROMO1, mitochondria lose the inner membrane YME1L protease, which participates in OPA1 processing and ROMO1 turnover. While ROMO1 is dispensable for general protein import along the presequence pathway, we show that it participates in the dynamics of TIM21 during respiratory chain biogenesis and is specifically required for import of YME1L. | 30598479 |
| 2018-09-01 10:44:00 | Data show that engineered YME1L protease discriminates between degradation signals by amino acid composition, implying the use of sequence-specific signals in mitochondrial proteostasis. | 27786171 |
| 2017-10-07 10:27:00 | These results identify mutations in YME1L1 as a cause of a mitochondriopathy with optic nerve atrophy highlighting the importance of YME1L1 for mitochondrial functionality in humans. | 27495975 |
| Type | IDs |
|---|---|
| Synonymous | FTSH, MEG4, OPA11, PAMP, YME1L |
| Gene |
UniProtKB-ID:
YMEL1_HUMAN
UniprotKB:
Q96TA2
UniParc:
UPI00001A4E52,
UPI000013DBDD,
UPI0000001C16
EMBL:
AY358484,
AF151782,
AJ132637,
BC023507,
AL160291,
BC024032,
AK297973,
CH471072,
AL162272
Ensembl:
ENSG00000136758
KO:
hsa:10730
|
| Nucleutide sequences |
EMBL-CDS:
EAW86071.1,
BAG60283.1,
EAW86070.1,
CAB51858.1,
AAK57555.1,
EAW86068.1,
EAW86072.1,
AAH24032.1,
AAQ88848.1,
AAH23507.1,
EAW86069.1
Gene_ORFName:
UNQ1868/PRO4304
Ensembl_TRS:
ENST00000376016,
ENST00000613434,
ENST00000326799
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000318480,
ENSP00000365184,
ENSP00000481724
RefSeq:
XP_011517602.1,
NP_055078.1,
NP_001240795.1,
NP_647473.1
|
| Others |
UniRef100:
UniRef100_Q96TA2
UniRef90:
UniRef90_Q96TA2
UniRef50:
UniRef50_Q96TA2
UniGene:
Hs.74647,
Hs.499145
CCDS:
CCDS7152.1,
CCDS58072.1,
CCDS7151.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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