| Type | Description |
|---|---|
| Definition | O-GlcNAcase |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity. | 33086728 |
| 2020-06-20 10:39:00 | Study reports that OGA is upregulated in a wide range of human cancers and drives aerobic glycolysis and tumor growth by inhibiting pyruvate kinase M2 (PKM2). PKM2 is dynamically O-GlcNAcylated in response to changes in glucose availability. Under high glucose conditions, PKM2 is a target of OGA-associated acetyltransferase activity, which facilitates O-GlcNAcylation of PKM2 by O-GlcNAc transferase (OGT). | 31501520 |
| 2020-03-28 12:47:00 | role of the tubular biomarkers NAG, kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin in patients with chest pain before contrast media exposition | 30920848 |
| 2019-04-27 11:01:00 | OGT promotes carcinogenesis and metastasis of cervical cancer cells. OGT's expression is significantly upregulated in cervical cancer, and low OGT level is correlated with improved prognosis | 30052810 |
| 2018-02-10 10:41:00 | Beta-N-acetylhexosaminidase substrate recognition and specificity | 28939839 |
| Type | IDs |
|---|---|
| Synonymous | MEA5, MGEA5, NCOAT |
| Gene |
UniProtKB-ID:
OGA_HUMAN
UniprotKB:
O60502
UniParc:
UPI0000073533,
UPI000187B6C7,
UPI00000706F3,
UPI00004563F9
EMBL:
AF036144,
BC039583,
AC010789,
CH471066,
BC047877,
AB014579,
BC001343,
AF307332
Ensembl:
ENSG00000198408
KO:
hsa:10724
|
| Nucleutide sequences |
EMBL-CDS:
AAH47877.1,
AAG21428.1,
EAW49742.1,
AAH01343.1,
AAD05385.2,
AAH39583.2,
BAA31654.2,
EAW49741.1,
EAW49744.1
Ensembl_TRS:
ENST00000439817,
ENST00000357797,
ENST00000361464,
ENST00000370094
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359112,
ENSP00000354850,
ENSP00000409973,
ENSP00000350445
RefSeq:
XP_016871075.1,
NP_001135906.1,
XP_024303550.1,
XP_016871074.1,
NP_036347.1
|
| Others |
UniRef100:
UniRef100_O60502
UniRef90:
UniRef90_Q8VIJ5
UniRef50:
UniRef50_Q8VIJ5
UniGene:
Hs.500842
CCDS:
CCDS7520.1,
CCDS44471.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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