| Type | Description |
|---|---|
| Definition | solute carrier family 12 member 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:06:00 | SLC12A ion transporter mutations in sporadic and familial human congenital hydrocephalus. | 31393094 |
| 2020-05-23 12:56:00 | The IGF1 gene was amplified in 9 of 19 ACC samples, similar to findings in The Cancer Genome Atlas database. The IGF1 overexpression was observed in 5 samples and was associated with SLC12A7 overexpression and non-functional, early-stage tumors (p < 0.05). endogenous overexpression and silencing of SLC12A7 significantly altered IGF1 and IGF1R expression without impacting other IGFs. | 31034883 |
| 2019-05-18 11:51:00 | SLC12A7 alters adrenocortical carcinoma cell adhesion properties to promote an aggressive invasive behavior | 29884238 |
| 2016-05-28 10:25:00 | SLC12A7 gene amplification and overexpression occurs frequently in adrenocortical carcinoma and may play a role in adrenocortical carcinoma tumorigenesis. | 26454676 |
| 2012-01-07 10:47:00 | The Wnk3 protein isoforms have a similar effect on SLC12 cotransporters. NKCC1/2 and NCC were inhibited, even in hypertonicity, while KCCs were activated, even in isotonic conditions. | 21613606 |
| Type | IDs |
|---|---|
| Synonymous | KCC4 |
| Gene |
UniProtKB-ID:
S12A7_HUMAN
UniprotKB:
Q9Y666
UniParc:
UPI000002B30E,
UPI0000141815
EMBL:
AC116351,
BC007760,
AL117433,
AF105365,
AK024497,
BC098390,
AK024493
Ensembl:
ENSG00000113504
KO:
hsa:10723
|
| Nucleutide sequences |
EMBL-CDS:
AAD39741.1,
AAH98390.1,
AAH07760.1,
BAB15787.1,
BAB15783.1,
CAB55921.1
Ensembl_TRS:
ENST00000264930
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264930
RefSeq:
XP_011512242.1,
XP_016864447.1,
NP_006589.2,
XP_011512243.2,
XP_011512241.1,
XP_016864448.1,
XP_005248288.1
|
| Others |
UniRef100:
UniRef100_Q9Y666
UniRef90:
UniRef90_Q9Y666
UniRef50:
UniRef50_Q9Y666
UniGene:
Hs.172613
CCDS:
CCDS34129.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员