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10721 POLQ

10721

POLQ

DNA polymerase theta

protein-coding

Homo sapiens

基因描述

Type Description
Definition DNA polymerase theta

研究结论

Date Results Publications
2021-04-17 13:15:00 Human DNA polymerase theta harbors DNA end-trimming activity critical for DNA repair. 33577776
2021-01-02 12:49:00 The roles of polymerases nu and theta in replicative bypass of O (6)- and N (2)-alkyl-2'-deoxyguanosine lesions in human cells. 32098870
2020-12-26 13:13:00 Genetic evidence for reconfiguration of DNA polymerase theta active site for error-free translesion synthesis in human cells. 32169903
2020-11-21 13:27:00 Mutant POLQ and POLZ/REV3L DNA polymerases may contribute to the favorable survival of patients with tumors with POLE mutations outside the exonuclease domain. 32838755
2020-10-31 13:20:00 POLQ suppresses interhomolog recombination and loss of heterozygosity at targeted DNA breaks. 32873648

名称对应

Type IDs
Synonymous PRO0327
Gene
UniProtKB-ID: DPOLQ_HUMAN, Q59EE4_HUMAN
UniprotKB: O75417, Q59EE4
UniParc: UPI0000D61B5F, UPI00004F6E78, UPI0000E5A89A
EMBL: AY338826, AF052573, AC069239, AC079841, AB209867, AF043628
Ensembl: ENSG00000051341
KO: hsa:10721
Nucleutide sequences
EMBL-CDS: AAD05272.1, AAR08421.2, AAC33565.1, BAD93104.1
Ensembl_TRS: ENST00000264233
Protein sequencees
Ensembl_PRO: ENSP00000264233
RefSeq: NP_955452.3
Others
UniRef100: UniRef100_Q59EE4, UniRef100_O75417
UniRef90: UniRef90_O75417
UniRef50: UniRef50_O75417
UniGene: Hs.241517
CCDS: CCDS33833.1

全选

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研究热度

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