| Type | Description |
|---|---|
| Definition | ceramide synthase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-13 14:14:00 | Single nucleotide polymorphisms in the gene LASS1 associated with programmed cell death, providing a potential cellular mechanism for the effects on tissue damage and circulating Creatine kinase. | 26913518 |
| 2013-05-04 12:33:00 | This study highlights a close interaction between CLN5/CLN8 proteins, and their role in sphingolipid metabolism. Our findings suggest that CLN5p/CLN8p most likely are positive modulators of CerS1 and/or CerS2. | 23160995 |
| 2012-07-07 11:23:00 | Moreover, an alternatively spliced variant CerS1 mRNA (CerS1-2) was detected mainly in cancer cells or primary tumour tissues compared to controls, which was targeted by miR-574-5p for degradation | 22180294 |
| 2011-02-05 10:37:00 | The variation in LASS1 is functional, causing enhanced expression of the gene, and it contributes to healthy aging and greater survival in the tenth decade of life. | 20569235 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | 20569235 |
| Type | IDs |
|---|---|
| Synonymous | EPM8, GDF-1, GDF1, LAG1, LASS1, UOG1 |
| Gene |
UniProtKB-ID:
CERS1_HUMAN,
Q5XG75_HUMAN,
B4DE47_HUMAN
UniprotKB:
P27544,
Q5XG75,
B4DE47
UniParc:
UPI000012E98A,
UPI000002AD72,
UPI00017A6C69,
UPI00002037D6
EMBL:
AF105006,
AF105005,
AC005197,
M62302,
AF105008,
AF105009,
AK293463,
BC022450,
AC003972,
AF105007,
BC084582
Ensembl:
ENSG00000223802
KO:
hsa:10715
|
| Nucleutide sequences |
EMBL-CDS:
AAD16892.1,
AAC24611.1,
AAA58500.1,
AAH22450.1,
AAH84582.1,
BAG56958.1
Ensembl_TRS:
ENST00000623882,
ENST00000429504,
ENST00000542296
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000485308,
ENSP00000389044,
ENSP00000437648
RefSeq:
NP_001374368.1,
NP_067090.1,
NP_001374370.1,
NP_001277194.1,
NP_001374369.1,
NP_001374373.1,
NP_001374371.1,
NP_937850.1,
NP_001374374.1,
NP_001374372.1
|
| Others |
UniRef100:
UniRef100_B4DE47,
UniRef100_P27544,
UniRef100_Q5XG75
UniRef90:
UniRef90_A0A2K5IYM6,
UniRef90_P27544
UniRef50:
UniRef50_P27544,
UniRef50_W5PLI4
UniGene:
Hs.412355
CCDS:
CCDS46021.1,
CCDS46020.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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