| Type | Description |
|---|---|
| Definition | DNA polymerase delta 3, accessory subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:33:00 | Polymerase delta promotes chromosomal rearrangements and imprecise double-strand break repair. | 33077594 |
| 2020-03-21 10:35:00 | telomeric R-loops promote repair of telomeric DSBs through CSB-RAD52-POLD3-mediated BIR, a previously unknown pathway protecting telomeres from duanyu1670-induced telomeric SSBs may not only give rise to DSBs indirectly, but also promote DSB repair by inducing R-loops, revealing an unexpected interplay between distinct duanyu1670-induced DNA lesions. | 31777915 |
| 2018-06-16 11:14:00 | findings demonstrate a key role of POLD1 and POLD3 in genome stability and S-phase progression revealing RNA-DNA hybrids-dependent effects for POLD3 that might be partly due to its Pol zeta interaction. | 27974823 |
| 2017-10-28 11:24:00 | The proofreading activity of DNA polymerase delta plays a role in shunting DNA mismatch repair to an EXO1-dependent excision pathway as opposed to directly participating in gap formation via its 3'-5' exonuclease activity. | 28934474 |
| 2017-09-09 11:43:00 | The mitotic DNA synthesis is RAD52 dependent, and RAD52 is required for the timely recruitment of MUS81 and POLD3 to common fragile sites in early mitosis. | 27984745 |
| Type | IDs |
|---|---|
| Synonymous | P66, P68, PPP1R128 |
| Gene |
UniProtKB-ID:
DPOD3_HUMAN,
A0A024R5M8_HUMAN
UniprotKB:
Q15054,
A0A024R5M8
UniParc:
UPI00005DC72A,
UPI000012973E,
UPI00005DC72B
EMBL:
AK316301,
AP001324,
BC108908,
BC108909,
D26018,
CH471076,
AP001104,
AP001372
Ensembl:
ENSG00000077514
KO:
hsa:10714
|
| Nucleutide sequences |
EMBL-CDS:
EAW74942.1,
AAI08909.1,
AAI08910.1,
BAH14672.1,
BAA05039.1,
EAW74943.1
Gene_ORFName:
hCG_27408
Ensembl_TRS:
ENST00000263681,
ENST00000532497,
ENST00000527458
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263681,
ENSP00000436018,
ENSP00000432951
RefSeq:
XP_005273773.1,
NP_001350526.1,
XP_011543036.1,
NP_006582.1
|
| Others |
UniRef100:
UniRef100_Q15054
UniRef90:
UniRef90_Q15054
UniRef50:
UniRef50_Q15054
UniGene:
Hs.82502
CCDS:
CCDS86228.1,
CCDS8233.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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